Molecular genetics in medicine : advances, applications and ethical implications : proceedings of the Twenty-Sixth Annual Symposium of the Galton Institute, London, 1989

書誌事項

Molecular genetics in medicine : advances, applications and ethical implications : proceedings of the Twenty-Sixth Annual Symposium of the Galton Institute, London, 1989

edited by D.F. Roberts and Robert Chester

(Studies in biology, economy and society)

Macmillan in association with the Galton Institute, 1991

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

The rapid increase in knowledge of human genetics in recent decades and the spectacular advances in molecular genetics in the 1980s, have already brought remarkable benefits, particularly in the detection of inherited disease pre-natally or pre-symptomatically. But the new techniques have brought with them a host of other problems - ethical, legal, political, psychological. This book reports the proceedings of the Galton Institute's symposium exploring some of these issues. It concentrates on the applications of molecular genetic techniques in clinical genetics, setting these against the background of the experience of existing practice. The volume sketches recent advances in knowledge at the chromosome and molecular levels, how this new knowledge is used to prevent or treat, the benefits brought and expected, and the implications of these practices for the family and society. The book reveals coherence in present policies and sympathetic applications of them in current use, and so provides an introduction to the principles and practice of modern clinical genetics in the United Kingdom.

目次

  • Introduction, D.F.Roberts
  • the human chromosome map, T.Andrews
  • the DNA map, Kay E.Davies
  • molecular individuality and genetic "Fingerprinting", C.F.Inglehearn and R.J.Bellamy
  • fetal tissue sampling, R.J.Lilford
  • fetal tissue sampline, R.J.Lilford
  • fetal diagnosis and the need for support, K.M.Laurence
  • prospects for gene insertion therapy in early life, Marcus Pembrey
  • neural transplantation in degenerative disease, E.R.Hitchcock
  • population screening for genetic disorder, Sarah Bundey
  • family screening and molecular prediction - lessons from huntington's disease, Peter S.Harper and Michael J.Morris
  • molecular genetics in medicine - sharing the benefits, Trefor Jenkins
  • genetic registers - problems old and new, Alan E.H.Emer
  • new problems in management of families, A.Clarke
  • law or ethics?, D.J.Cusine
  • tensions - the ethics of choice, G.R.Dunstan.

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