Central neural mechanisms in cardiovascular regulation

著者

書誌事項

Central neural mechanisms in cardiovascular regulation

George Kunos, John Ciriello, editors

Birkhaüser, c1991-

  • [v. 1] : alk. pbk.
  • [v. 1] : alk. pbk.
  • v. 2 : alk.
  • v. 2 : alk.

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注記

[v. 1] based on lectures at a symposium of the 13th Scientific Meeting of the International Society of Hypertension held in June 1990, in Bethesda, Md

Includes bibliographical references and index

内容説明・目次

巻冊次

[v. 1] : alk. pbk. ISBN 9780817635459

内容説明

With the help of recent technological advances in the study of cen- tral nervous system function, important strides have been made in our knowledge regarding the pathophysiology of high blood pres- sure. The understanding of neural mechanisms involved in the reg- ulation of the cardiovascular system is of critical importance to the development of rational approaches to both the treatment and pre- vention of this disease. It was in this spirit that a satellite symposium of the 13th Scientific Meeting of the International Society of Hyper- tension was held in June 1990, in Bethesda, Maryland. The chapters, in this first of two volumes on the same general theme, are based on lectures presented at the symposium and it is hoped that these sum- maries of recent research findings from prominent laboratories around the world will provide a stimulus for future research. The symposium would not have been possible without generous support from the National Institute on Alcohol Abuse and Alcoholism, Merck Frosst Canada, G. D. Searle Co. , Squibb Institute of Medical Research, Smith, Kline & Beecham Co. , Pfizer Co. , E. I. Dupont de Nemours Co. , Merck, Sharp & Dohme Co. , The UpJohn Co. , and Wyeth-Ayerst Co. While this volume was being prepared for publication, one of its contributors, Dr. Michael J. Brody, died suddenly. It is with deep sorrow and sympathy that we mourn the loss of our colleague. Dr.

目次

Section I Ventral Medullary Mechanisms.- 1. Afferent Inputs to Ventrolateral Medulla.- 2. Widespread Autonomic Afferents to the Nucleus Paragigantocellularis of the Rostral Ventrolateral Medulla.- 3. Regulation of Autonomic Cardiovascular Function by the Rostral Ventromedial Medulla.- 4. Flexibility of the Map of Brainstem Neurons with Sympathetic Nerve-Related Activity.- 5. Imidazole Receptors and their Endogenous Ligand in the Rostral Ventrolateral Medulla: Relationship to the Action of Clonidine on Arterial Pressure.- 6. The Role of the Rostral Ventrolateral Medulla in the Synchronization of Respiratory and Sympathetic Functions.- Section II Central Neurotransmitter Systems.- 7. Interaction of Angiotensin II with Catecholamines in the Brain.- 8. Actions of Angiotensin II in the Ventrolateral Medulla Oblongata.- 9. Cardiovascular Actions of Angiotensin II in the Ventrolateral Medulla.- 10. Endorphinergic Neurons in the Brainstem: Role in Cardiovascular Regulation.- 11. Endogenous Opioid Peptides, Glucocorticoids, and Shock: Specificity, Site, and Mechanism of Action.- 12. Neuropeptides in Central Baroreceptor Reflex Pathways.- 13. Adenosine in Central Cardiovascular Control.- Section III Control of Sympathetic Tone, Hypertensive Mechanisms.- 14. Spinal Mechanisms in the Sympathetic Control of Cardiac Function.- 15. The Function of Catecholamines in the Control of Sympathetic Preganglionic Neurons.- 16. Contribution of Forebrain Structures to the Development of Neurogenic Hypertension.- 17. Mechanisms of Differential Cardiovascular Responsiveness to 2-Deoxyglucose-Induced Central Glycopenia in Conscious Spontaneously Hypertensive and Wistar Kyoto Rats.- 18. High-Renin Renal Hypertension Depresses the Baroreflex Control of Heart Rate and Sympathetic Activity.- 19. Opioidergic-Dopaminergic Interaction in Hypertension.
巻冊次

v. 2 : alk. ISBN 9780817635695

内容説明

High blood pressure disease is one of the most prevalent pathological conditions in modem society with potentially serious consequences. During the last two decades major progress has been made in the development of rational approaches to the treatment of high blood pressure. A key factor in this progress has been an increase in our understanding of how the brain controls blood pressure. The chapters in the present book, together with those in a previous volume, provide a broad overview of recent progress in our knowledge of the central neural mechanisms involved in the regulation of the cardiovascular system. It is our hope that these essays by leading experts in the field will not only provide a useful source of information, but will also stimulate inquiry leading to new discoveries in this critically important field of research. George Kunos John Ciriello vii List of Contributors Jeffrey J. Anderson, Department of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana 46208, USA Katsuyuki Ando, Fourth Department of Internal Medicine, University of Tokyo School of Medicine, Tokyo 112, Japan Jaideep S. Bains, Department of Physiology, Queen's University, Kingston, Ontario, Canada K7L 3N6 Kathleen H. Berecek, Department of Physiology and Biophysics and the Vascular Biology and Hypertension Program, The University of Alabama at Birmingham, Birmingham, Alabama 35294, USA Vernon S. Bishop, Department of Physiology, The University of Texas Health Science Center, San Antonio, Texas 78284-7756, USA P. A.

目次

1 Role of Vasopressin in Central Cardiovascular Regulation.- 2 Central Neural Mechanisms in the Cardiovascular Response to Exercise.- 3 Hypothalamic Mechanisms and the Cardiovascular Response to Stress.- 4 Circumventricular Organs and Cardiovascular Homeostasis.- 5 Centrally Mediated Cardiovascular Effects of Taurine.- 6 Central Catecholamines and the Control of Sympathetic Tone.- 7 Role of Excitatory Amino Acids and Their Receptors in Bulbospinal Control of Cardiovascular Function.- 8 Respiratory-Sympathetic Integration in the Medulla Oblongata.- 9 Tachykinins, Tachykinin Receptors, and the Central Control of the Cardiovascular System.- 10 Natriuretic Peptide System in the Brain and Its Implication in Central Cardiovascular Regulation.- 11 Central Neural Mechanisms in the Cardiovascular Effects of Ethanol.- 12 Interactions Between Cardiovascular and Pain Regulatory Systems.- 13 Brain Stem GABA Pathways and the Regulation of Baroreflex Activity.- 14 GABAB Receptors in the Nucleus Tractus Solitarius in Cardiovascular Regulation.- 15 Baroreflexes in Hypertension.

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