The New genetics of mental illness

著者

書誌事項

The New genetics of mental illness

edited by Peter McGuffin and Robin Murray

Butterworth-Heinemann , Mental Health Foundation, 1991

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Expanding on a theme of a conference organized by the Mental Health Foundation, this volume is a synthesis of the recent and rapid developments in molecular biology and genetics which impinge upon clinical practice in mental illness. The implications of new discoveries in these fields for a whole range of intractable conditions are immense. Schizophrenia, Alzheimer's disease, manic-depressive illness, Huntington's chorea, autism and certain anxiety states may all prove to be preventable and treatable as a result of multi-disciplinary co-operation in basic and clinical science. The contributions to the book come from North America, Europe and the UK and represent some of the key work currently being undertaken. The text will be of benefit to clinical and research psychiatrists, and to those with interests in molecular genetics, biochemistry and neuropharmacology.

目次

  • The cell, molecular biology and the new genetics, S.Whatley and M.Owen
  • genetic models of madness, P.McGuffin
  • the uses and abuses of linkage analysis in neuro-psychiatric disorder, F.Clerget-Darpoux
  • the formal problems of linkage, J.Edwards
  • schizophrenia - how far can we go in defining the phenotype, A.Farmer et al
  • schizophrenia - classical approaches with new twists and provocative results, I.Gottesman and A.Bertelsen
  • genetic linkage studies of schizophrenia, H.Gurling et al
  • aberrant neurodevelopment as the expression of the schizophrenia genotype, P.Jones and R.Murray
  • the familial aggregation of affective disorders - relation to symptom severity and social provocation, P.Bebbington et al
  • life events and depressive symptoms - a twin study perspective, K.Kendler et al
  • genetic markers and affective disorders, P.McGuffin and M.Sargeant
  • the genetics of vulnerability to alcoholism, S.Hodgkinson et al
  • genes and the aetiology of eating disorders, J.Treasure and A.Holland
  • growing together and growing apart - the non-genetic forces on children in the same family, R.Goodman
  • autism as a genetic disorder, M.Rutter
  • learning disability and psychiatric/behavioural disorders - a genetic perspective, A.Holland
  • the genetics of the common forms of dementia, A.Wright
  • the molecular basis of Alzheimer's dimentia, J.Hardy
  • prediction and prevention in Huntingdon's Disease, M.Morris and P.Harper.

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