α-adrenoceptors : molecular biology, biochemistry, and pharmacology
著者
書誌事項
α-adrenoceptors : molecular biology, biochemistry, and pharmacology
（Progress in basic and clinical pharmacology, vol. 8）
Karger, 1991
- : acid-free paper
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
The advances made in our understanding of the molecular structure and physiological function of beta-and alpha-adrenoceptors have led to an additional appreciation of the roles that these receptors play in homeostasis and in pathological states. As a result, the beta-and alpha-adrenoceptor sub-types have become increasingly important drug targets due to their critical roles in the etiology, pathology and treatment of disease. This volume reviews the current status of beta-adrenoceptors and alpha-adrenoceptors from the standpoint of molecular biology, biochemistry and pharmacology. The contents span the entire spectrum of research from the intracellular level of the nucleus, through the biochemical processes activated or inhibited by these receptors, to the functional effects they mediate in organs, animals and ultimately in humans, both in normal and disease states.
目次
- Alpha-adrenoceptor subclassification
- molecular biology of alpha-adrenoceptors
- alpha-adrenoceptor signal transduction mechanisms
- structure-activity relationships for alpha-adrenoceptor agonists and antagonists
- functions mediated by alpha-adrenoceptors
- therapeutic applications of agents
- interfacing with alpha-adrenoceptors.
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