The natural killer cell
著者
書誌事項
The natural killer cell
（The natural immune system）
IRL Press at Oxford University Press, c1992
- : hbk
- : pbk
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注記
Includes bibliographical references and index
内容説明・目次
- 巻冊次
-
: pbk ISBN 9780199632329
内容説明
The ability of an organism to combat infection by foreign particles and microbial pathogens is essential for its survival and evolutionary success. Such efforts at immunity can take two forms. A considerable number of works have been published which focus on the central role of antigen recognition and antibody structure and function in the host response to infection. This volume, however, discusses the recent shift in focus towards the "natural" or "innate" immune system which consists of various cell types and factors. These cells and factors can take part in immune responses without prior sensitization, and have important modulatory effects on later, specific responses. This work reviews the biology and function of the natural killer cell, covering such topics as the molecular basis of natural killer cell function and its role in viral infection, tumor biology, and transplantation. Graduate students and researchers in immunology, cell biology, and medicine will find this work a valuable resource on current research in this exciting field.
目次
- The biology of natural killer cells, J. O'Shea and J.R. Ortaldo
- natural killer cells in haematopoiesis, G. Trinchieri
- natural killer cells in bacterial injection, P. Garcia-Penarrubia
- natural killer cells in viral infection, R.M. Welsh and M. Vargas-Cortes
- natural killer cells in transplantation, P.C. Hogan
- natural killer cells in tumour biology, C.E. Lewis and J.O'D. McGee
- natural killer cells / large granualar lymphocytes in pregnancy, P.M. Starkey.
- 巻冊次
-
: hbk ISBN 9780199632336
内容説明
The ability of an organism to combat infection by foreign particles and microbial pathogens is essential for its survival and evolutionary success. Such efforts at immunity can take two forms. A considerable number of works have been published which focus on the central role of antigen recognition and antibody structure and function in the host response to infection. There has, however, recently been a shift in focus towards the "natural" or "innate" immune system, which consists of various cell types and factors. These cells and factors can take part in immune responses without prior sensitization, and have important modulatory effects on later, specific responses. This volume is devoted to reviewing the biology and function of the natural killer cell A range of topics is covered, such as the molecular basis of natural killer cell function, its role in viral infection, tumour biology, and transplantation.
目次
- The biology of natural killer cells, J. O'Shea and J.R. Ortaldo
- natural killer cells in haematopoiesis, G. Trinchieri
- natural killer cells in bacterial injection, P. Garcia-Penarrubia
- natural killer cells in viral infection, R.M. Welsh and M. Vargas-Cortes
- natural killer cells in transplantation, P.C. Hogan
- natural killer cells in tumour biology, C.E. Lewis and J.O'D. McGee
- natural killer cells / large granualar lymphocytes in pregnancy, P.M. Starkey.
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