Pharmaceutical inhalation aerosol technology
著者
書誌事項
Pharmaceutical inhalation aerosol technology
（Drugs and the pharmaceutical sciences, v. 54）
Marcel Dekker, Inc., c1992
- : alk. paper
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This broadly based reference - edited by a leading researcher with a varied background in both the pharmaceutical and medicinal aspects of aerosol technology - covers all aspects of aerosol therapy and offers logical development of important concepts to organize comprehensively the body of knowledge in this multidisciplinary field.
Discussing in detail the physiologic, pharmacologic, metabolic, and physicochemical factors influencing the effective use of pharmaceutical aerosols, "Pharmaceutical Inhalation Aerosol Technology": provides methods of generation, administration, and characterization; clarifies how to overcome obstacles that interfere with successful drug delivery; describes pharmaceutical aerosols in a variety of therapeutic contexts; examines packaging of metered-dose inhalers and approaches to particle size characterization; shows clinical applications of the technology and delineates the major products, their uses, and limitations; explains the development of a delivery system for pentamidine for the treatment of "Pneumocystis carinii" pneumonia in AIDS patients; and illustrates recent clinical developments and future therapeutic uses of aerosols delivered to the lung. "Pharmaceutical Inhalation Aerosol technology" is for industrial, clinical, and research pharmacists; medicinal and pharmaceutical chemists; pulmonologists and allergists; environmental scientists; aerosol researchers; and upper-level undergraduate and graduate students in these disciplines.
目次
- Factors governing aerosol deposition and targeting in the lung - physiology of the airways, Anthony J. Hickey and David C. Thompson, pharmacology of therapeutic aerosols, David C. Thompson, targeting by deposition, Igor Gonda, drug targeting to the lung - chemical and biochemical considerations, Peter A. Crooks
- methods of generation, administration, and characterization of aerosols - theoretical principles and devices used to generate aerosols for research, Keng H. Leong, the design and development of inhalation drug delivery systems, Paul J. Atkins, et al, aerosol-filling equipment for the preparation of pressurized pack pharmaceutical formulations, Christophe Sirand, et al, methods of aerosol particle size characterization, Anthony J. Hickey, summary of common approaches to pharmaceutical aerosol administration, Anthony J. Hickey
- clinical aspects of aerosol administration and future perspectives - therapeutic aerosols - an overview from a clinical perspective, F. Charles Hiller, aerosolized pentamidine for treatment and prophylaxis of pneumocystis carinii pneumonia in patients with acquired immunodeficiency syndrome, A. Bruce Montgomery, modulated drug therapy with inhalation aerosols, Ralph W. Niven.
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