書誌事項

Glycine neurotransmission

edited by Ole P. Ottersen and Jon Storm-Mathisen

Wiley, c1990

大学図書館所蔵 件 / 5

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Glycine stands today as brain and has long since ceased to be regarded as a "private" transmitter of the spinal cord. Recent research has not only given evidence that glycine acts as a transmitter in many supraspinal regions, such as the cochlear nuclei, cerebellum and retina, but its effect on the NDA receptor opens the possibility that glycine or related substances influence synaptic transmission throughout the brain. Knowledge about the latter effect of glycine will undoubtedly be exploited in attempts to develop new therapeutic strategies for neurological diseases. The aim of this book is to give an up-to-date review of the recent advances in basic research on glycine. The authors hope that the book will convey to the reader an image of a dynamic research field, which offers potentialities for a better understanding of brain function in general.

目次

  • The discovery of the neurotransmitter role of glycine, M.H.Aprison
  • the biochemistry of glycinergic neurons, E.C.Daly
  • molecular structure and developmental regulation of the inhibitory glycine receptor, D.Langosch et al
  • immunocytochemical localization of the glycine receptor, A.Tiller et al
  • patch-clamp studies of glycine-gated chloride channels, J.Bormann
  • quantitative electrophysiological studies and modeling of central glycinergic synapses, H.Korn and D.S.Faber
  • glycine - and GABA-activated chloride conductances in lamprey neurons, A.R.Martin
  • involvement of glycine in excitatory neurotransmission, E.J.Fletcher et al
  • glycine modulation of NMDA receptors - autoradiographic studies, D.T.Monaghan
  • autoradiograhic mapping of glycine receptors by strychnine binding, R.Cortes and J.M.Palacies
  • electron microscopic autoradiographic studies on glycine uptake in spinal cord and cerebellum, G.Wilkin et al
  • antibodies and fixatives for the immunocytochemical localization of glycine, J.Storn-Mathisen and O.P.Ottersen
  • cellular and subcellular localization of glycine studied by quantitative electron microscopic immunocytochemistry, O.P.Ottersen et al
  • the anatomy, development, physiology and role of glycinergic neurons in the xenopus embryo spinal cord, N.Dale et al
  • autoradiographic and immunocytochemical studies of glycine-containing neurons in the retina, R.G.Pourcho and D.J.Goebel
  • immunocytochemistry of glycine and glycine receptors in the central auditory system, R.J.Wenthold and C.Hunter
  • colocalization of glycine-like and GABA-like immunoreactivities - a semiquantitative study of individual neurons in the dorsal cochlear nucleus of cat, K.K.Osen et al
  • electrophysiological studies of glycinergic mechanisms in auditory brain stem structures, D.M.Caspary.

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