Nuclear processes and oncogenes

著者

    • Bristol-Myers Squibb Symposium on Cancer Research (14th : 1990 : Massachusetts Institute of Technology)

書誌事項

Nuclear processes and oncogenes

edited by Phillip A. Sharp

（Bristol-Myers Squibb cancer symposia / editor Stephen K. Carter, v. 14）

Academic Press, c1992

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注記

Based on the 14th Bristol-Myers Squibb Symposia on Cancer Research, held on Sept. 24, 1990 at Massachusetts Institute of Technology

Includes bibliographical references and index

内容説明・目次

内容説明

Reviews recent advances in the functions and structures of nuclear proteins encoded by oncogenes and tumour suppressor genes. This book also explores the relationship between the biochemical properties of these proteins and regulation of transcription.

目次

  • Part 1 Nuclear oncogenes: oncogenes, tumor suppressor genes and the deregulation of cell growth - an overview, R.A. Weinberg
  • the functions of MYB and MYC, J.M. Bishop
  • transcriptional regulation of fos and jun, T. Curran, et al
  • transformation by v-erbA and v-erB modulation of differentiation and proliferation in erythroid progenitors, H. Beug, et al. Part 2 Nuclear tumor supressor genes: the p53 gene and gene product, R.S. Quartin, et al
  • the p53 gene in human cancer, S.J. Baker and B. Vogelstein
  • the retinoblastoma protein is regulated by the cdc2 kinase, Q. Hu, et al
  • cellular proteins that can interact specifically with the retinoblastoma susceptibility gene product, W.G. Kaelin, Jr., et al
  • the role of the WT1 tumor suppressor gene in the ediology of wilm, D.E. Housman
  • tumor. Part 3 Regulation of transcription: the serum response element - structure and function, R. Treisman
  • the mouse H19 gene - its structure and function in mouse development, S.M. Tilghman, et al
  • regulation of transcription in animal cells - factors and mechanisms, B.F. Pugh and R. Tjian.

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