Polycystic kidney disease
Author(s)
Bibliographic Information
Polycystic kidney disease
(Contributions to nephrology, v. 97)
Karger, c1992
Available at 4 libraries
  Aomori
  Iwate
  Miyagi
  Akita
  Yamagata
  Fukushima
  Ibaraki
  Tochigi
  Gunma
  Saitama
  Chiba
  Tokyo
  Kanagawa
  Niigata
  Toyama
  Ishikawa
  Fukui
  Yamanashi
  Nagano
  Gifu
  Shizuoka
  Aichi
  Mie
  Shiga
  Kyoto
  Osaka
  Hyogo
  Nara
  Wakayama
  Tottori
  Shimane
  Okayama
  Hiroshima
  Yamaguchi
  Tokushima
  Kagawa
  Ehime
  Kochi
  Fukuoka
  Saga
  Nagasaki
  Kumamoto
  Oita
  Miyazaki
  Kagoshima
  Okinawa
  Korea
  China
  Thailand
  United Kingdom
  Germany
  Switzerland
  France
  Belgium
  Netherlands
  Sweden
  Norway
  United States of America
Note
Includes bibliographical references and index
Description and Table of Contents
Description
Polycystic kidney disease (PKD) is one of the most frequent and expensive genetic diseases. Based on an international workshop, this volume brings together the findings of research groups working in close collaboration on PKD. A number of papers review experimental models of cystic kidney disease and scrutinize the relevance of these models for autosomal dominant PKD, the most common form of human PKD. Further papers discuss the early treatment of hypertension and low-protein diets as potential methods to delay the progression of chronic renal failure. Focus is also placed on the progress of genetic studies towards isolation of the PKD1 gene on chromosome 16. An extensive study to assess the extent of genetic heterogeneity of autosomal dominant PKD in Europe is reported. This data is of prime importance for the use of DNA markers for early diagnosis of PKD. A computer program for quick drawing of pedigrees and analysis of linkage is described.
Table of Contents
- Polycystic kidney disease - thoughts on the meaning of prevention, K. Zerres
- regulation of cell proliferation and fluid secretion in the progressive enlargement of renal cysts, J.J. Grantham
- pathophysiology of renal tubular cyst formation in murine models of polycystic kidney disease, W.E. Sweeney and E.D. Avner
- rat models of polycystic kidney disease, N. Gretz et al
- a model of polycystic kidney disease in SBM transgenic mice, M. Trudel and V. D'Agati
- a chimaeric mouse model for autosomal-dominant polycystic kidney disease, C.A. Boulter et al
- autosomal-dominant polycystic kidney disease and hypertension - a review, K.W. Florijn et al
- effect of a low-protein diet on the rate of progression of chronic renal failure in patients with polycystic kidney disease, N. Gretz and M. Strauch
- the molecular genetics of autosomal-dominant polycystic kidney disease of the PKD1 type, S. Somlo et al
- isolation and characterization of a candidate gene for autosomal-dominant polycystic kidney disease, S.L. Graw et al
- MEGABASE/PKD - a genetic database for polycystic kidney disease, L.A. Sandkuijl
- genetic heterogeneity of polycystic kidney disease in Europe, D.J.M. Peters and L.A. Sandkuijl.
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