Transition metal complexes of naturally occurring nucleobases and their derivatives

Bibliographic Information

Transition metal complexes of naturally occurring nucleobases and their derivatives

editors, James R. Lusty, Peter Wearden & Virtudes Moreno

(CRC handbook of nucleobase complexes, v.2)

CRC Press, c1992

Other Title

Handbook of nucleobase complexes

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Note

Includes bibliographical references and indexes

Description and Table of Contents

Description

This handbook describes methods of preparation, characterization, toxicity, and therapeutic indices of transition metal complexes of the naturally occurring heterocyclic nucleobases and their derivatives. Modes of coordination are listed together with the relevant spectral data and major methods of investigation. Where appropriate, the spectrum of the sample is included in the pertinent section on spectroscopy. Data on the uncomplexed bases, such as solubility, pK, accepted structure(s) in the solid state and solutions, and the natural occurrence of the base are also included. Volume II of this work provides the spectroscopic data to accompany Volume I. Volume II is divided into two sections: Section 1 summarizes the data and Section 2 is comprised of figures. In Section 1, the complexes are arranged according to the method of study. In Section 2, figures are listed by base type and follow the sequence of Volume I, mainly complexes of the pyrimidine bases, nucleosides and nucleotides, and then purine bases, nucleosides, and nucleotides.

Table of Contents

METHODS OF STUDY. Antitumor Activity. Circular Dichorism. Conductivity. Electron Spin Resonance Spectroscopy. High Performance Liquid Chromatography. Infrared Spectroscopy. Mossbauer Spectroscopy. 1H Nuclear Magnetic Resonance. 13C Nuclear Magnetic Resonance. 31P Nuclear Magnetic Resonance. 195 Pt Nuclear Magnetic Resonance. pK Measurements. Raman Spectroscopy. Thermal Studies. UV-VIS Spectroscopy. XPS. X-Ray. Figures. References.

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