Animal models in toxicology
著者
書誌事項
Animal models in toxicology
（Drug and chemical toxicology, v. 8）
M. Dekker, c1992
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Providing step-by-step procedures specifically adapted to each of the major animal model species and describing the basic in vivo techniques used in toxicology and pharmacology, this single-source reference presents the information necessary to select appropriate in vivo models, design experiments, and interpret experimental results.;Furnishing physiological, preproductive, histopathological, clinical pathology, and anaesthesia data for the major laboratory species, Animal Models in Toxicology supplies a historical overview; discusses proper dosing techniques; examines common background diseases; details distinctive metabolic characteristics; demonstrates how to extrapolate results; and explicates animal welfare regulations.;With over 2600 literature citations and an appendix that lists the major commercial sources of laboratory animals, Animal Models in Toxicology is a comprehensive reference for toxicologists, pharmacologists, physiologists, and biochemists in pharmaceutical, clinical, biotechnology and contract laboratories; laboratory animal scientists and technicians; and upper-level undergraduate and graduate courses in animal pharmacology, experimental toxicology, comparative physiology, and experimental procedure.
目次
- Introduction, Christopher P. Chengelis and Shayne Cox Gad. Part 1 The rat: toxicology, David E. Semler
- pathology, Shayne Cox Gad
- metabolism, Christopher P. Chengelis. Part 2 The mouse: toxicology, James M. Andress
- pathology, Charles H. Frith et al
- metabolism, Chyung S. Cook. Part 3 The hamster: toxicology, Anne C. Costello
- pathology, Frederick G. Hess
- metabolism, Christopher P. Chengelis. Part 4 The guinea pig: toxicology, Shayne Cox Gad
- pathology, John C. Peckham
- metabolism, Christopher P. Chengelis. Part 5 The rabbit: toxicology, Clare M. Salamon and Karen M. MacKenzie
- pathology, Robert R. Dahlgren
- metabolism, Chyung S. Cook. Part 6 The ferret: toxicology, Daniel E. McLain and Richard M. Hoar
- pathology, Glen K. Miller
- metabolism, Christopher P. Chengelis. Part 7 The dog: toxicology, Gillian C. Haggerty
- pathology, Robert W. Thomassen
- metabolism, Christopher P. Chengelis. Part 8 Nonhuman primates: toxicology, Gene B. Fuller et al
- pathology, Curtis D. Port
- metabolism, Christopher P. Chengelis. Alternative species, Christopher P. Chengelis
- clinical pathology of laboratory animals, Robert L. Hall
- model selection and scaling, Shayne Cox Gad
- susceptibility factors, Shayne Cox Gad
- laws and regulations governing animal care and use in research, Curtis D. Port
- appendix - commercial sources of laboratory animals, Shayne Cox Gad.
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