Animal models in toxicology

著者

書誌事項

Animal models in toxicology

edited by Shayne Cox Gad, Christopher P. Chengelis

（Drug and chemical toxicology, v. 8）

M. Dekker, c1992

大学図書館所蔵 件 / 全6件

この図書・雑誌をさがす

注記

Includes bibliographical references and index

内容説明・目次

内容説明

Providing step-by-step procedures specifically adapted to each of the major animal model species and describing the basic in vivo techniques used in toxicology and pharmacology, this single-source reference presents the information necessary to select appropriate in vivo models, design experiments, and interpret experimental results.;Furnishing physiological, preproductive, histopathological, clinical pathology, and anaesthesia data for the major laboratory species, Animal Models in Toxicology supplies a historical overview; discusses proper dosing techniques; examines common background diseases; details distinctive metabolic characteristics; demonstrates how to extrapolate results; and explicates animal welfare regulations.;With over 2600 literature citations and an appendix that lists the major commercial sources of laboratory animals, Animal Models in Toxicology is a comprehensive reference for toxicologists, pharmacologists, physiologists, and biochemists in pharmaceutical, clinical, biotechnology and contract laboratories; laboratory animal scientists and technicians; and upper-level undergraduate and graduate courses in animal pharmacology, experimental toxicology, comparative physiology, and experimental procedure.

目次

  • Introduction, Christopher P. Chengelis and Shayne Cox Gad. Part 1 The rat: toxicology, David E. Semler
  • pathology, Shayne Cox Gad
  • metabolism, Christopher P. Chengelis. Part 2 The mouse: toxicology, James M. Andress
  • pathology, Charles H. Frith et al
  • metabolism, Chyung S. Cook. Part 3 The hamster: toxicology, Anne C. Costello
  • pathology, Frederick G. Hess
  • metabolism, Christopher P. Chengelis. Part 4 The guinea pig: toxicology, Shayne Cox Gad
  • pathology, John C. Peckham
  • metabolism, Christopher P. Chengelis. Part 5 The rabbit: toxicology, Clare M. Salamon and Karen M. MacKenzie
  • pathology, Robert R. Dahlgren
  • metabolism, Chyung S. Cook. Part 6 The ferret: toxicology, Daniel E. McLain and Richard M. Hoar
  • pathology, Glen K. Miller
  • metabolism, Christopher P. Chengelis. Part 7 The dog: toxicology, Gillian C. Haggerty
  • pathology, Robert W. Thomassen
  • metabolism, Christopher P. Chengelis. Part 8 Nonhuman primates: toxicology, Gene B. Fuller et al
  • pathology, Curtis D. Port
  • metabolism, Christopher P. Chengelis. Alternative species, Christopher P. Chengelis
  • clinical pathology of laboratory animals, Robert L. Hall
  • model selection and scaling, Shayne Cox Gad
  • susceptibility factors, Shayne Cox Gad
  • laws and regulations governing animal care and use in research, Curtis D. Port
  • appendix - commercial sources of laboratory animals, Shayne Cox Gad.

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