Animal models in toxicology
著者
書誌事項
Animal models in toxicology
（Drug and chemical toxicology, v. 8）
M. Dekker, c1992
大学図書館所蔵 全6件
注記
Includes bibliographical references and index
内容説明・目次
内容説明
Providing step-by-step procedures specifically adapted to each of the major animal model species and describing the basic in vivo techniques used in toxicology and pharmacology, this single-source reference presents the information necessary to select appropriate in vivo models, design experiments, and interpret experimental results.;Furnishing physiological, preproductive, histopathological, clinical pathology, and anaesthesia data for the major laboratory species, Animal Models in Toxicology supplies a historical overview; discusses proper dosing techniques; examines common background diseases; details distinctive metabolic characteristics; demonstrates how to extrapolate results; and explicates animal welfare regulations.;With over 2600 literature citations and an appendix that lists the major commercial sources of laboratory animals, Animal Models in Toxicology is a comprehensive reference for toxicologists, pharmacologists, physiologists, and biochemists in pharmaceutical, clinical, biotechnology and contract laboratories; laboratory animal scientists and technicians; and upper-level undergraduate and graduate courses in animal pharmacology, experimental toxicology, comparative physiology, and experimental procedure.
目次
- Introduction, Christopher P. Chengelis and Shayne Cox Gad. Part 1 The rat: toxicology, David E. Semler
- pathology, Shayne Cox Gad
- metabolism, Christopher P. Chengelis. Part 2 The mouse: toxicology, James M. Andress
- pathology, Charles H. Frith et al
- metabolism, Chyung S. Cook. Part 3 The hamster: toxicology, Anne C. Costello
- pathology, Frederick G. Hess
- metabolism, Christopher P. Chengelis. Part 4 The guinea pig: toxicology, Shayne Cox Gad
- pathology, John C. Peckham
- metabolism, Christopher P. Chengelis. Part 5 The rabbit: toxicology, Clare M. Salamon and Karen M. MacKenzie
- pathology, Robert R. Dahlgren
- metabolism, Chyung S. Cook. Part 6 The ferret: toxicology, Daniel E. McLain and Richard M. Hoar
- pathology, Glen K. Miller
- metabolism, Christopher P. Chengelis. Part 7 The dog: toxicology, Gillian C. Haggerty
- pathology, Robert W. Thomassen
- metabolism, Christopher P. Chengelis. Part 8 Nonhuman primates: toxicology, Gene B. Fuller et al
- pathology, Curtis D. Port
- metabolism, Christopher P. Chengelis. Alternative species, Christopher P. Chengelis
- clinical pathology of laboratory animals, Robert L. Hall
- model selection and scaling, Shayne Cox Gad
- susceptibility factors, Shayne Cox Gad
- laws and regulations governing animal care and use in research, Curtis D. Port
- appendix - commercial sources of laboratory animals, Shayne Cox Gad.
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