Neural transplantation : a practical approach
Author(s)
Bibliographic Information
Neural transplantation : a practical approach
（The practical approach series）
IRL Press : Oxford University Press, c1992
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Note
Includes bibliographical references and index
Description and Table of Contents
- Volume
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p/b ISBN 9780199632855
Description
This is a practical introduction to the techniques of neural transplantation in mammalian brain tissue. It provides a detailed description of the techniques, written by acknowledged experts in the field, with practical details and hints complementing the underlying principles. Each chapter identifies the equipment needed, the preparations to be made in advance and step-by-step protocols for each procedure. All aspects of neural transplantation surgery are covered, from staging and dissection of embryonic CNS tissues, through the preparation of tissues for implantation, to the transplant surgery itself. A variety of different methods for solid and cell suspension transplantation are covered. Specialized chapters consider genetic engineering of cells, labelling of grafts, and other aspects of tissue manipulation in culture prior to implantation; implantation of PNS and gilal tissues; transplantation in neonatal animals, including primates; handling of human embryonic tissues for transplantation and immunological considerations.
The book should be of interest to neuroscientists studying neural development, anatomical plasticity, functional organization and recovery in the mammalian CNS and to neurologists and neurosurgeons interested in developing clinical applications of neural transplantation. It should be stressed that these techniques are experimental and not for clinical use yet.
Table of Contents
- Preface
- S.B. Dunnett and A. Bjorklund: Staging and diessection of rat embryos
- M.D. Kawaja, L.J. Fisher, M. Schinstine, H.A. Jinnah, J. Ray, L.S. Chen, and F.H. Gage: Grafting genetically modified cells within the rat CNS
- A. Bjorklund and S.B. Dunnett: Neural transplantation in adult rats
- R.D. Lund and K.T. Yee: intracerebral transplantation to immature hosts
- M. Vidal-Sanz, G.M. Bray, and A.J. Aguayo: The use of peripheral nerve grafts to study CNS regeneration
- W.F. Blakemore and A.J. Crang: Transplantation of glial cells into areas of demyelinatin in the adult rat spinal cord
- L.E. Annett, and R.M Ridley: Neural transplantation in primates
- P. Brundin: Dissection, preparation, and implantation of human embryonic brain tissue
- R.D. Lund and R. Bannerjee: Immunological considerations in neural transplantation
- J. Cadusseau and M. Peschanski: Identifying grafted cells.
- Volume
-
h/b ISBN 9780199632862
Description
This is a practical introduction to the techniques of neural transplantation in mammalian brain tissue. It provides a detailed description of the techniques, written by acknowledged experts in the field, with practical details and hints complementing the underlying principles. Each chapter identifies the equipment needed, the preparations to be made in advance and step-by-step protocols for each procedure. All aspects of neural transplantation surgery are covered, from staging and dissection of embryonic CNS tissues, through the preparation of tissues for implantation, to the transplant surgery itself. A variety of different methods for solid and cell suspension transplantation are covered. Specialized chapters consider genetic engineering of cells, labelling of grafts, and other aspects of tissue manipulation in culture prior to implantation; implantation of PNS and gilal tissues; transplantation in neonatal animals, including primates; handling of human embryonic tissues for transplantation and immunological considerations.
The book should be of interest to neuroscientists studying neural development, anatomical plasticity, functional organization and recovery in the mammalian CNS and to neurologists and neurosurgeons interested in developing clinical applications of neural transplantation. It should be stressed that these techniques are experimental and not for clinical use yet.
Table of Contents
- Staging and dissection of rat embryos, S.B. Dunnett
- grafting genetically modified cells within the rat CNS, M.D. Kawaja et al
- neural transplantation in adult rats, A. Bjorklund and S.B. Dunnett
- intracerebral transplantation to immature hosts, R.D. Lund and K.T. Yee
- the use of peripheral nerve grafts to study CNS regeneration, M. Vidal-Sanz et al
- transplantation of glial cells into areas of demyelination in the adult rat spinal cord, W.F. Blakemore and A.J. Crang
- neural transplantation in primates, L.E. Annett and R.M. Ridley
- dissection, preparation and implantation of human embryonic brain tissue, P. Brundin
- immonological considerations in neural transplantation, R.D. Lund and R. Bannerjee
- identifying grafted cells, J, Cadusseau and M. Peschanski.
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