Biological significance of superantigens

著者

• Fleischer, B. (Bernhard)

書誌事項

Biological significance of superantigens

volume editor, Bernhard Fleischer

（Chemical immunology, vol. 55）

Karger, c1992

注記

Includes bibliographical references and index

内容説明・目次

内容説明

This publication describes the so-called superantigens, the most potent stimulators of T lymphocytes known. Superantigens induce shock, immunosuppression and T cell tolerance and are involved in the pathogenesis of certain infectious diseases. Leading investigators present the latest findings on the molecular genetics, the immunology and the biological and clinical significance of these novel molecules. Topics covered in the reviews include the molecular biology of superantigens from "staphylococcus aureus" and "streptococcus pyogenes", the mitogen of "mycoplasma arthritidis", the biology of superantigens encoded by mouse mammary tumour viruses, the pathogenesis of toxic shock syndrome, as well as T cell energy and immunosuppression as a consequence of interaction of superantigens with the immune system. Updating progress in a fast-moving area of research, this book should be of benefit to immunologists working with T lymphocytes, microbiologists interested in bacterial toxins, and medical doctors studying the pathogenetic role of T lymphocytes.

目次

• Staphylococcal toxic shock syndrome - toxin and streptococcal pyrogenic exotoxins - a comparative study of their molecular biology, M.J. Betley et al
• T lymphocyte stimulation by microbial superantigens, B. Fleischer and U. Hartwig
• retroviral superantigens, H. Acha-Orbea
• mis antigens - immunity and tolerance, S.R. Webb, et al
• effects of staphylococcal toxins on T-cell activity in vivo, A. Ochi, et al
• mycoplasma arthritidis-derived superantigens, L. Rink and H. Kirchner
• cellular and molecular mechanisms of immune activation by microbial superantigens - studies using toxic shock syndrome toxin-1, T. Chatila, et al
• T-cell-dependent shock induced by a bacterial superantigen, T. Miethke, et al
• germ-line-encoded recognition of certain short peptide antigens, W. Born, et al.

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詳細情報

• NII書誌ID(NCID): BA18431276
• ISBN:
  • 3805555873
• 出版国コード: sz
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: Basel ; Tokyo
• ページ数/冊数: x, 200 p.
• 大きさ: 25 cm
• 件名:
  • MESH : Antigens, Bacterial -- physiology
  • MESH : Antigens, Viral -- physiology
  • MESH : Enterotoxins -- immunology
  • MESH : Shock, Septic -- etiology
  • MESH : T-Lymphocytes -- immunology
• 親書誌ID:
  • BA07831443