Regulation of isopentenoid metabolism

著者

書誌事項

Regulation of isopentenoid metabolism

W. David Nes, Edward J. Parish, James M. Trzaskos, editor[s]

(ACS symposium series, 497)

American Chemical Society, 1992

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注記

"Developed from a symposium sponsored by the Division of Agricultural and Food Chemistry at the 201st National Meeting of the American Chemical Society, Atlanta, Georgia, April 14-19, 1991"

Includes bibliographical references and indexes

内容説明・目次

内容説明

Presents the current state of isopentenoid metabolism in plants, animals, and insects. Illustrates cross-disciplinary research efforts by the medical and agricultural communities to solve common problems regarding the regulation of the isopentenoid pathway. Addresses the rational design of potent inhibitors specific to different regulatory steps. Examines the chemical, biochemical, and molecular biological mechanisms that regulate the pathway. Covers newly emerging areas, including prenylated proteins and cancer, carotenoids and biotechnology, sterol homeostasis, and molecular biology.

目次

  • Biosynthesis and Utilization of Isoprenoids
  • Regulation of Isopentenoid Metabolism
  • Monoterpene Biosynthesis in Conifer Defense
  • Natural Rubber Biosynthesis
  • Production of Natural Carotenoids
  • Prenylated Amino Acid Composition of Tissues
  • Isoprenylation of Nucleotide-Binding Proteins
  • Inhibitors of Squalene Synthase
  • Oxysterol Regulation of Cholesterol Biosynthesis
  • Dual-Action Inhibitors of Cholesterol Biosynthesis
  • Regulation of Sterol Biosynthesis
  • Oxysterols in Plants, Animals, and Microorganisms
  • Sterol Biosynthesis Inhibitors as Agrochemicals
  • Target Enzymes for Sterol Biosynthesis Inhibitors
  • Squalene Epoxidase Inhibitors
  • Inhibition of Sterol Metabolism
  • Cytochrome P450-Dependent 14*a-Demethylase
  • Effect of Tridemorph on Sterol Synthesis in Algae
  • Sphingomyelin in Cellular Cholesterol Homeostasis
  • Genes Functioning Late in the Sterol Biosynthetic Pathway

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