Epidemiology and biology of multiple myeloma
著者
書誌事項
Epidemiology and biology of multiple myeloma
Springer-Verlag, c1991
- : gw
- : us
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注記
Based on a workshop held at the National Institutes of Health on Mar. 27, 1990 and sponsored by the National Cancer Institute
Includes bibliographical references
内容説明・目次
内容説明
This volume is the result of a workshop, sponsored by the National Cancer Institute in March 1990, which explored the epidemiology of multiple myeloma. The papers included in this volume address differences in immunologic factors and in risk factors for multiple myeloma between blacks and whites, describe the monoclonal gammopathies and their progression to myeloma, and speculate on hypotheses regarding the etiology and pathogenesis of this challenging malignancy. Questions that are addressed include whether neoplastic change occurs at the level of the plasma cell or earlier in the B-cell lineage, the role of inappropriate gene expression, the importance of IL-6 production, and new findings regarding the cytogenetics of this malignancy. Key directions for new research on multiple myeloma and related malignancies are also suggested.
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