Serotonin receptor subtypes : pharmacological significance and clinical implications
著者
書誌事項
Serotonin receptor subtypes : pharmacological significance and clinical implications
（International Academy for Biomedical and Drug Research, vol. 1）
Karger, 1992
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This volume on serotonin receptor subtypes is the first in a new series dedicated to providing up-to-date analyses of major therapeutic areas by the world's leading experts. In the last ten years there has been an explosion of interest in serotonin receptors and their classification, in part because new drug tools have led to a better understanding of their structure and function, but also because of the potential to find new medicines in this area. The contributions presented here discuss and evaluate current developments related to both basic science aspects and clinical applications in the field of serotonin receptor subtypes.
目次
- Molecular analysis of serotonin receptor subtypes, R.L. Weinshank
- 5-HT1 receptor subtypes - pharmacological heterogeneity, M.C. Miguel and M. Hamon
- 5HT2-receptors - location, pharmacological, pathological and physiological role, J.E. Leysen
- pharmacological relevance of 5-HT3 receptors, J.R. Fozard
- uptake mechanisms and drug development, R.W. Fuller
- animal models of anxiety and aggression in the study of serotonergic agents, B. Olivier et al
- electrophysiological evidence for the distinct properties of presynaptic and postsynaptic 5-HT1A receptors - possible clinical relevance, C. de Montigny and P. Blier
- current concepts of the role of serotonin function in depression and anxiety, D.S. Charney and P.L. Delgado
- different 5-HT receptors modulate glutamate release in cerebellum (5-HT1 and 5-HT2) and cholecystokinin release in nucleus accumbens (5-HT3) - possible relevance to cerebellar ataxias and to anxiety, M. Raiteri et al
- serotonin and eating disorders - pharmacological relationships, G. Curzon
- 5-hydroxytryptamine receptors and drug discovery, P.P.A. Humphrey.
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