書誌事項

Purines : pharmacology and physiological roles

edited by T.W. Stone

(Satellite symposia of the IUPHAR 9th International Congress of Pharmacology)

VCH, 1985

  • VHC Verlag
  • VHC Publisher

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注記

Includes bibliographies and indexes

内容説明・目次

内容説明

Twenty-five papers presented at a Satellite Symposium of the 9th IUPHAR Congress focus on purine receptors and the interactions of purines with adenylate cyclase. Among the topics discussed are the structures of purine receptors in both the central nervous system and in peripheral tissue, the pharmacological effects of purines in the nervous system, the possibilities of a modulation of adenylate cyclase, and the effects of purines on cell growth and differentiation.

目次

  • Summary of a Symposium Discussion on Purine Receptor Nomenclature
  • Adenosine Receptors in the Central Nervous System: Structure$Activity Relationships for Agonists and Antagonists
  • Characterization of Adenosine Receptors in the Hippocampus and other Regions of Rat Brain
  • Behavioral Actions of Adenosine Analogues
  • The Pharmacology of Purines in the CNS: Interactions with Psychoactive Agents
  • Actions of Purines in Autonomic Ganglia
  • Processes by which Purines Inhibit Transmitter Release
  • Are There Two Types of Adenosine Receptors in Peripheral Tissues?
  • Structure$Activity Relationship Studies of Adenosine Analogues in Peripheral Tissues: Implications for Receptor Classification and Structure
  • Release of ATP from Central and Peripheral Nerve Terminals
  • Metabolism and Release of Purines from Nervous Tissue
  • Uptake of ATP by Tissues
  • Adenosine and the Cardiovascular System: Some of the Problems and Controversies
  • Metabolic Regulation of Cerebral Blood Flow by Adenosine
  • Purines and Hypertension
  • Purines and Hypertension: Interaction with Hydralazine
  • Actions and Structure$Activity Relationships of Purines on Platelets
  • Adenosine as a Putative Mediator in Asthma: Its Role in Broncho-constriction and Modulation of Histamine Release from Human Lung Mast Cells and Basophil Leucocytes
  • Modulation of Adenylate Cyclase by Physiological and Pharmacological Manipulation of the Prevalent Adenosine Concentration
  • Ligand Binding to Adenosine Receptors and the Inhibition of Adenylate Cyclase
  • Magnesium Ions Exert a Central Role in Integrating Adenosine Receptor Occupancy with the Inhibition of Adenylate Cyclase
  • The Endogenously Formed Adenosine of the Brain: Its Status as a Regulatory Signal Appraised in Relation to Actions of Homocysteine
  • Regulation of Lipolysis and Circulation in Adipose Tissue
  • Effects of Purines on Cell Growth and Differentiation
  • Some Unresolved Problems.

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