Down syndrome and Alzheimer disease : proceedings of the National Down Syndrome Society Conference on Down Syndrome and Alzheimer Disease, held in New York, January 16 and 17, 1992
Author(s)
Bibliographic Information
Down syndrome and Alzheimer disease : proceedings of the National Down Syndrome Society Conference on Down Syndrome and Alzheimer Disease, held in New York, January 16 and 17, 1992
(Progress in clinical and biological research, v. 379)
Wiley-Liss, c1992
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Note
Includes bibliographical references and index
Description and Table of Contents
Description
Over the last decade, biomedical researchers have documented that individuals with Downs syndrome have a markedly high probability of developing Alzheimer disease in later life. This book presents a comprehensive overview of current research efforts aimed at understanding the behavioural, neuropathological, and genetic correlations between Downs syndrome and Alzheimer disease. As a survey of current knowledge on the subject, the book includes both clinical analyses and experimental approaches to offer a full perspective on the subject.
Table of Contents
- ALZHEIMER DISEASE IN DOWN SYNDROME: The Neurology of Alzheimer Disease in Down Syndrome
- Longitudinal Study of Neuropsychological Function in Older Adults With Down Syndrome
- Dementia in Down Syndrome: Methods of Evaluation
- Parallels Between Down Syndrome Dementia and Alzheimer's Disease
- Down Syndrome: Differentiating Mental Retardation and Dementia With Brain Imaging Techniques
- Down Syndrome as a Key to the Time Sequence of Brain Changes in Alzheimer Disease
- RELATIONSHIP OF CHROMOSOME 21 TO ALZHEIMER DISEASE AND AMYLOID: Amyloid Precursor Protein (APP) and A4 Amyloid in Alzheimer's Disease and Down Syndrome
- Mutations in APP and Their Role in beta-Amyloid Deposition
- MODEL SYSTEMS AND PATHOGENETIC MECHANISMS: Neurodegeneration and Gene Dysregulation: Studies Utilizing the Mouse Trisomy 16 Model of Down Syndrome
- Alzheimer's Disease-Type Brain Abnormalities in Animal Models
- Potential Role of S100-beta in Alzheimer's Disease: An Hypothesis Involving Mitotic Protein Kinases. @21 YC4, S
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