Malignancy and acquired abnormalities

著者

    • Rooney, D. E. (Densie E.)
    • Czepulkowski, B. H. (Barbara H.)

書誌事項

Malignancy and acquired abnormalities

edited by D.E. Rooney and B.H. Czepulkowski

(The practical approach series, Human cytogenetics : a practical approach ; v. 2)

IRL Press, c1992

2nd ed

  • : hbk
  • : pbk

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注記

Includes bibliographical references

内容説明・目次

巻冊次

: pbk ISBN 9780199632893

内容説明

Acquired chromosome abnormalities are associated with cancer and leukaemia, exposure to some chemicals and radiation and some rare diseases. This volume is a laboratory manual of techniques for the cytogenetic study of these disorders.

目次

  • B.H. Czepulkowski & B. Bhatt, & D.E. Rooney: Basic techniques for the preparation and analysis of chromosomes from bone marrow and leukaemic blood
  • A.M. Potter & A. Watmore: Cytogenetics in myeloid leukaemia
  • B. Gibbons, & B.H. Czepulkowski: Cytogenetics in acute lymphoblastic leukaemia
  • C.J. Harrison: The lymphomas and chronic lymphoproliferative disorders
  • B. Bain: The role of cytogenetics in the assessment of haematological disorders
  • N. Mandahl: Methods in solid tumour cytogenetics
  • E.J. Tawn & D. Holdsworth: Mutation-induced chromosome damage in human lymphocytes
  • R.T. Howell & A.M.R. Taylor: Chromosome instability syndromes
  • J.K. Cowell: Somatic cell hybrids in the analysis of the human genome
  • D.M. Lillington, F.E. Cotter, & P. N. Riddle: Microdissextion of human metaphase chromosomes
  • Appendix
  • Index.
巻冊次

: hbk ISBN 9780199632909

内容説明

Acquired chromosome abnormalities are associated with malignancy, exposure to mutagenic agents, and some chromosome instability syndromes. Their study often entails extensive modification of standard cytogenetic techniques as well as a very different approach to analysis. "Human Cytogenetics - A Practical Approach: Volume II" is a comprehensive manual of techniques for the study of acquired chromosome abnormalities, and as such a source of information for cytogeneticists, haematologists, and oncologists alike. Since the interpretation of chromosome preparations is notoriously difficult in some of these conditions, illustrations, both diagrammatic and photographic, of all chromosome rearrangements discussed are an important feature of this book. In addition to basic techniques, the book takes a futuristic look at new technology which is becoming important in the study of cytogenetics, particularly in the field of cancer research.

目次

  • Basic techniques for the preparation of chromosomes from bone marrow and leukaemic blood, B.H. Czepulkowski et al
  • cytogenetics in myeloid leukaemia, A.M. Potter and A. Watmore
  • cytogenetics in acute lymphoblastic leukaemia, B. Gibbons and B.H. Czepulkowski
  • the lymphomas and chronic lymphopropliferative disorders, B. Bain
  • methods in solid tumour cytogenetics, N. Mandahl
  • mutation-induced chromosome damage in human lymphocytes, E.J. Tawn and D. Holdworth
  • chromosome instability syndromes, R.T. Howell and A.M.R. Taylor
  • somatic cell hybrids in the analysis of the human genome, J.k. Cowell
  • microdissextion of human metaphase chromosomes, D.M. Lillington et al.

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