Calculation of drug lipophilicity : the hydrophobic fragmental constant approach
Author(s)
Bibliographic Information
Calculation of drug lipophilicity : the hydrophobic fragmental constant approach
VCH, c1992
- : Weinheim
- : New York
- Other Title
-
Drug lipophilicity
Available at 3 libraries
  Aomori
  Iwate
  Miyagi
  Akita
  Yamagata
  Fukushima
  Ibaraki
  Tochigi
  Gunma
  Saitama
  Chiba
  Tokyo
  Kanagawa
  Niigata
  Toyama
  Ishikawa
  Fukui
  Yamanashi
  Nagano
  Gifu
  Shizuoka
  Aichi
  Mie
  Shiga
  Kyoto
  Osaka
  Hyogo
  Nara
  Wakayama
  Tottori
  Shimane
  Okayama
  Hiroshima
  Yamaguchi
  Tokushima
  Kagawa
  Ehime
  Kochi
  Fukuoka
  Saga
  Nagasaki
  Kumamoto
  Oita
  Miyazaki
  Kagoshima
  Okinawa
  Korea
  China
  Thailand
  United Kingdom
  Germany
  Switzerland
  France
  Belgium
  Netherlands
  Sweden
  Norway
  United States of America
Note
Spine title: Drug lipophilicity
Includes bibliographical references (p. [105]-110) and index
Description and Table of Contents
Description
Comprehensive and comparative, this "cookbook" gives the ingredients and recipes for setting up lipophilicity calculations of a great variety of organic molecules. Of particular interest is the extended presentation of the yet unpublished, revised version of the sigma f-lipophilicity calculation procedure (REKKER-system). Calculation examples of 36 drugs familiarize the user quickly with the calculation method and allow a comparative quality proof. The useful monograph unites the features of a textbook with those of a handbook for academic and industrial scientists. It gives students an exceptionally clear presentation of the subject and helps scientists save time in the laboratory.
Table of Contents
- Importance of lipophilicity in QSAR studies
- calculation of log P values
- intramolecular aspects of lipophilitic behaviour
- tables of fragmental constants
- log-P calculations for selected drugs.
by "Nielsen BookData"