Bibliographic Information

Chiral separations by liquid chromatography

Satinder Ahuja, editor

(ACS symposium series, 471)

American Chemical Society, 1991

Available at  / 16 libraries

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Note

"Developed from a symposium sponsored by the Division of Analytical Chemistry at the 200th National Meeting of the American Chemical Society, Washington, D.C., August 26-31, 1990."

Includes bibliographical references and indexes

Description and Table of Contents

Description

A definitive reference for researchers working on problems involving chirality. Presenting state-of-the-art information, this volume covers all the major modes of separation and offers contributions from the leading researchers who developed these techniques. Four chapters provide a detailed review of the commonly used columns: brush type, cyclodextrin, polysaccaride carbonate, and protein. Many of the papers focus on HPLC, a technique which is also ideally suited for large scale preparation of optical isomers. In addition, the volume provides significant discussion on the use of chiral discriminators or selectors.

Table of Contents

  • Chiral Separations: Overview
  • Analytical Criteria for Chiral High-Pressure Liquid Chromatography
  • Commercially Available Brush-Type Chiral Selectors for the Direct Resolution of Enantiomers
  • Chiral Separations Using Native and Functionalized Cyclodextrin-Bonded Stationary Phases in High-Pressure Liquid Chromatography
  • Chromatographical Optical Resolution on Polysaccharide Carbamate Phases
  • Protein Column-Based Chiral Reversed-Phase Liquid Chromatography
  • Optimization of Chiral Separations on Silica-Bonded *a[1-Acid Glycoprotein by Mobile Phase Additives
  • Chiral Recognition on Biopolymer-Based High-Pressure Liquid Chromatographic Chiral Stationary Phases: A Case for Multiple Interaction Sites
  • Chiral Separations and Modes of Association of Hydrogen-Bonding Molecules
  • Liquid Chromatographical Separation of Enantiomers by Hydrogen-Bond Association
  • High-Pressure Liquid Chromatographic Resolution of Optical Isomers: Influence of Mobil and pi-Donor Chiral Stationary Phases
  • Direct Stereochemical High-Pressure Liquid Chromatographic Separation of Aminoglutethimide and Its Major Metbolite: Its Applications to Biological Fluids
  • Amino Acid Racemization: A Tool for Dating?

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