Excitatory amino acid receptors : design of agonists and antagonists

著者

書誌事項

Excitatory amino acid receptors : design of agonists and antagonists

editors, P. Krogsgaard-Larsen, J.J. Hansen

（Ellis Horwood series in pharmacological sciences）

E. Horwood, 1992

大学図書館所蔵 件 / 全5件

この図書・雑誌をさがす

注記

Includes bibliographical references and index

内容説明・目次

内容説明

Designed to reflect the growing awareness of the chemical aspects of excitatory amino acids, this text uses computer-based methods and X-ray techniques to depict and analyze molecules and structure-activity relationships. The book incorporates stereochemical principles into all analyses.

目次

  • Excitatory amino acids, excitotoxicity and neurodegenerative disorders
  • excitatory amino acid receptors - multiplicity and ligand specificity of receptor subtypes
  • isolation and structural characterization of excitatory amino acid receptors
  • electrophysiological techniques for the study of excitatory amino acids in mammalian neurones in slice preparations
  • receptor autoradiography of excitatory amino acid receptors - basic and clinical aspects
  • NMDA receptors - heterogeneity and agonism
  • sulphur - containing excitatory amino acids
  • competitive NMDA receptor antagonists
  • ligands for NMDA receptor modulatory sites
  • AMPA receptor agonists - structural, conformational and stereochemical aspects
  • quinoxalinediones as AMPA receptor antagonists - mechanism and structure activity studies
  • kainic acid receptor agonists
  • polyamine toxins as excitatory amino acid receptor ligands
  • L-AP4 receptor ligands
  • the quisqualate metabotropic receptor coupled to phospholipase C (Qp)
  • therapeutic opportunities in modulators of excitatory amino acid mediated neurotransmission.

「Nielsen BookData」 より

関連文献： 1件中  1-1を表示

詳細情報

ページトップへ