Growth factors of the vascular and nervous systems : functional characterization and biotechnology

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Bibliographic Information

Growth factors of the vascular and nervous systems : functional characterization and biotechnology

editors, C. Lenfant, R. Paoletti, A. Albertini

Karger, 1992

  • : alk. paper

Available at  / 3 libraries

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Note

"International Symposium on Biotechnology of Growth Factors: Vascular and Nervous Systems, Milan, May 13-15, 1991."--T.p

Includes bibliographical references and index

Description and Table of Contents

Description

Over the past two decades growth factors have been isolated and characterized in large numbers, and extensive progress has been made in the structural and functional characterization of cell surface receptors and intracellular components that mediate the effects of these factors. This book presents the latest research results of international groups actively involved in the study of cell and tissue responsiveness to growth factors. Results of special interest include data on the basic activity and molecular function of oncogenes of the "ras" family and of tyrosine kinases. The contributions discussing transforming growth factor beta and nerve growth factor contain much information for scientists interested in the application of basic research achievements to the therapy and cure of human diseases.

Table of Contents

  • The "ras" superfamily - post-translational modifications and functional regulation, A.I. Magee et al
  • transforming growth factor beta and growth suppression, J. Massague and M. Laiho
  • structure, function and regulation of protein tyrosine phosphatases, N.K. Tonks
  • PIGF - a gene coding for a novel human vascular permeability related protein, D. Maglione et al
  • cell surface activation of latent TGF beta, D.B. Rifkin et al
  • extracellular sequestration and release of fibroblast growth factor - a possible mechanism for indirect angiogenesis, I. Vlodavsky et al
  • cytokine modulation of endothelial cell interaction with tumour cell, D. Lauri and E. Dejana
  • adhesion molecules induced by cytokines on vascular endothelial cells, D.O. Haskard
  • regulation of nerve growth factor in cortical astrocytes and neurons by interleukin-1, phorbol ester and dexamethasone, B.C. Wise et al
  • synthesis and expression of recombinant human NGF in a mammalian cell line, C. Soranzo et al
  • nerve growth factor effects on the neuroimmunoendocrine system - a biobehavioural perspective, E. Alleva and L. Aloe
  • evidence for a role of nerve growth factor in the mammalian visual system, G. Carmignoto et al
  • nerve growth factor pharmacology in peripheral neuropathies - an outlook, G. Vantini et al
  • retinal ganglion neuronotrophic factor and its monoclonal antibody - functional studies, R.M.W. Chau et al
  • functional characterization of the glucocorticoid regulatory unit of the rat alpha-1-acid glycoprotein promoter, D. Di Lorenzo et al
  • insulin-like growth factor 1 and growth hormone levels in patients with type 1 diabetes mellitus, A. Giustina et al
  • biosynthesis of vasculotropin and expression of vasculotropin receptors by cultured cells, H. Moukadiri et al.

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