Artificial kidney, artificial liver, and artificial cells : [proceedings of the McGill Artificial Organs Research Unit international symposium, McGill University, April 20, 1977]

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Artificial kidney, artificial liver, and artificial cells : [proceedings of the McGill Artificial Organs Research Unit international symposium, McGill University, April 20, 1977]

edited by Thomas Ming Swi Chang

Plenum Press, c1978

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Includes bibliographical references and index

内容説明・目次

内容説明

There is a rapid increase in interest related to novel approaches in artificial kidneys, artificial liver, and detoxifi- cation. Recent research has included the successful clinical appli- cations of the principle of artificial cells for adsorbent hemo- perfusion. Since it is 20 years ago at McGill that the first report on "Artificial Cells" was presented, I thought it might be useful to get together a small group of speakers and participants for a day before the ASAIO meeting to discuss some recent advances in the area of the clinical applications of artificial kidney, artificial liver and artificial cells with emphasis on adsorbent hemoperfusion. However, the enthusiastic supports of distinguished speakers, session chairmen and participants were such that the original pro- jection of 100 participants had expanded to a preregistration total of 250, from Australia, Canada, England, France, Germany, Israel, Italy, Japan, The Netherlands, Scotland, Sweden and U. S. A. The program also expanded to include a review section on hemodialysis, dialysate regeneration, hemofiltration, resin hemoperfusion and oxystarch given by their respective originators. The remaining of the symposium emphasizes the status of the art on different encap- sulated adsorbent hemoperfusion approaches. I would like to apolo- gize to those who we could not accommodate beca~se of space limita- tions. It is hoped that this symposium volume may be useful for them and for others who are interested in this area. Special thanks are due to Ms Joanne Toms for her excellent secretarial assistance for the conference and Mrs.

目次

Address of Welcome.- Reviews of Hemodialysis, Dialysate Regeneration, Hemofiltration and Oxystarch.- The Present Status and Perspectives of Hemodialysis.- Current Status of Dialysate Regeneration for the Treatment of Chronic Uremia.- Devising a Practical Suitcase Hemodialyzer.- Present Status of Hemofiltration.- Oxystarch and Other Polyaldehydes: The Present Status in the Treatment of Uremia.- Microencapsulated Adsorbent Hemoperfusion.- Artificial Cells for Artificial Kidney, Artificial Liver and Detoxification.- Clinical Experience of Bead-Shaped Charcoal Haemoperfusion in Chronic Renal Failure and Fulminant Hepatic Failure.- Hepatic Assist System Using Bead-Type Charcoal.- Extracorporeal Immunoadsorbents for Specific Extraction of Circulating Immune Reactants.- Evaluation of Charcoal Hemoperfusion in Uremia.- Charcoal Hemoperfusion: Georgetown University Hospital Experience.- Treatment of Fulminant Hepatic Failure by Charcoal Haemoperfusion and Polyacrilonitrile Haemodialysis.- Use of Activated Adsorbent Haemoperfusion in Acute Intoxication.- Clinical Experience with Cellulose-Coated Carbon Hemoperfusion.- Hemoperfusion and Removal of Endogenous Uremic Middle Molecules.- Charcoal Hemoperfusion in Mushroom Poisoning: Amanita Phalloides.- Biocompatibility Studies of Hemoperfusion Systems for Liver and Kidney Support.- Other Adsorbent Hemoperfusion Approaches.- The Use of Membranes and Sorbents for Blood Detoxification: Cuprophan Sorbent Membranes.- Combination of Hemodialysis and Hemoperfusion in a Single Hollow-Fiber Unit for Treatment of Uremia.- The B-D Hemodetoxifier: Particulate Release and Its Significance.- Fixed-Bed Charcoal Hemoperfusion in the Treatment of Drug Overdose and Chronic Renal Failure.- Experience with Resin Hemoperfusion.- Strathclyde Approach Towards Artificial Kidney, Artificial Liver and Detoxification.- Communications.- Assessment of Two Rat Models of Fulminant Hepatic Failure for Testing Artificial Liver Devices.- Use of Albumin-Cellulose Nitrate Microencapsulated Charcoal Hemoperfusion: In Acute Digoxin Toxicity in Dogs.- Conversion of Urea and Ammonia to Amino Acid Using Sequential Enzymatic Reaction with Microencapsulated Multi-Enzyme Systems.- Microencapsulated Charcoal Hemoperfusion for Galactosemia.- The Filtration of Plasma from Whole Blood: A Novel Approach to Clinical Detoxification.- Ionsiv F-80 and Ionsiv W-85: Molecular Sieve Zeolite NH4+ Ion Exchangers for Removal of Urea Nitrogen.- Panel and General Discussions.- Chronic Renal Failure and Future Approaches.- Status of Artificial Liver Support: 1977.- Treatment of Acute Intoxication.- Interrelation of Hemoperfusion, Plasma Clearance and Half Life.- General Discussion.- Invited Speakers, Session Chairmen and Organizing Committee.

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