Inositol phosphates : chemical synthesis and biological significance

著者

    • Billington, David C.

書誌事項

Inositol phosphates : chemical synthesis and biological significance

David C. Billington

VCH Verlagsgesellschaft, c1993

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

This work provides a comprehensive review of the state of the art in the field of inositol phosphates, covering the chemical synthesis and biological significance of this important class of biomolecules which act as messengers in living organisms. Aimed at medicinal chemists, molecular biologists, physiologists, physiological chemists and biochemists, it features coverage of modern chemical methods (protection group techniques and resolution). It also offers an introduction to the biology behind the action of these molecules.

目次

  • Biochemistry, stereochemistry, and nomenclature of the inositol phosphates, R. Parthasarathy and F. Eisenberg Jr.
  • phosphoinositides and their stimulated breakdown, B.W. Agranoff and S.K. Fisher
  • enantiospecific synthesis and Ca2+ release activities of some inositol polyphosphates and their derivates, Clinton E. Ballou and Werner Tegge
  • synthesis of inositol polyphosphates and their derivatives, Shoichiro Ozaki and Yutaka Watanabe
  • synthesis of myo-inositol polyphosphates, Joseph P. Vacca, et al
  • preparation of optically active myo-inositol derivatives as intermediates for the synthesis of inositol phosphates, Trupti Desai, et al
  • pharmacological effects of d-myo-Inositol - 1,2,6-trisphosphate, M. Siren, et al
  • synthesis of new myo-inositol derivatives containing phosphate, sulfate and sulfonamido groups, Peter Westerduin and Constant A.A. van Boeckel
  • chemical modifications of inositol trisphosphates - tritiated, fluorinated and phosphate-tethered analogues, Glenn D. Prestwich and James F. Marecek
  • novel routes to inositol phosphates using pseudomonas putida oxidations of arenes, Stephen V. Ley, et al
  • enantiospecifric synthesis of inositol polyphosphates, phosphatidylinositides, and analogues from (-) - quinic acid, J.R. Falck and Abdelkrim Abdali
  • synthesis and complexation properties of inositol-phosphates, V.I. Shvets, et al
  • phosphorothioate analogues of phosphatidylinositol and inositol 1,2,-cyclic phosphate - application to the mechanism of phospholipase C, Karol S. Bruzik, et al
  • phosphorothioate analogues of D-myo-Inositol 1,4,5-trisphosphate - chemistry and biology, Barry V.L. Potter
  • synthesis and biological evaluation of inositol derivatives as inhibitors of phospholipase C, Franz Kaufmann, et al
  • synthesis and biological evaluation of inositol phospholipid analogues, John G. Ward and Rodney C. Young.

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