Arterial vasodilation : mechanisms and therapy

著者

書誌事項

Arterial vasodilation : mechanisms and therapy

edited by Michael F O'Rourke, Michel E Safar and Victor J Dzau

Edward Arnold, c1993

大学図書館所蔵 件 / 全4件

この図書・雑誌をさがす

注記

Includes index

内容説明・目次

内容説明

One of the most significant advances in therapeutic treatment in recent years is that of vasodilator therapy for treatment of cardiac failure, hypertension and angina pectoris. Vasodilator agents have been shown efficacious not only in alleviating symptoms of cardiac failure but also in reducing mortality in these conditions through dilation of the arteries, thus allowing greater blood flow. Successful as the therapies are, there have been few adequate explanations as to their mechanisms of action. This book discusses the therapeutic advances and assesses their theoretical basis. The mechanisms discussed have been largely neglected, yet an understanding of them helps explain the favourable actions of commonly used drugs.

目次

  • Function of conduit arteries
  • wave travel and reflection in the arterial system
  • effects of age and of hypertension on wave travel and reflections
  • effects of arterial disease on wave travel and reflection
  • modification of wave travel and reflection by vasodilator therapy
  • reduction or delay of wave reflections by vasodilator therapy as a strategy in management of hypertension, angina pectoris and ischaemic heart disease
  • effects of nitroglycerine on asending aortic impedance and on left ventricular loads in normal subjects and patients with coronary artery disease
  • effects of vasodilators on ascending aortic impedance and on left ventricular load in patients with cardiac failure at rest and exercise, and in hypertension
  • haemodynamic benefit of vasodilating beta-blocker compared to conventional beta-blocker in treatment of essential hypertension
  • difference between central and upper limb wave forms in man
  • what is the arterial pressure?
  • the response of arterial vessels to antihypertensive therapy - I basic concepts
  • the response of large arteries to antihypertensive treatment - II pharmacological aspects
  • the autonomic nervous system and large conduit arteries
  • effects of vasoactive drugs on coronary arteries, coronary artery stenoses and on collateral vessels
  • effects of vasodilator drugs on calibre and distensibility of small peripheral arteries
  • cellular mechanisms of vasodilation
  • nitrates - mechanisms of action and tolerance.

「Nielsen BookData」 より

詳細情報

ページトップへ