The Psychopharmacology and treatment of schizophrenia

Bibliographic Information

The Psychopharmacology and treatment of schizophrenia

edited by P.B. Bradley, S.R. Hirsch

(Oxford medical publications)(British Association for Psychopharmacology monograph, no. 8)

Oxford University Press, 1986

Available at  / 5 libraries

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Note

Includes bibliographies and index

Description and Table of Contents

Description

This book begins by discussing the basis of our understanding of drug treatment in schizophrenia, and the hypotheses derived from this. It then looks at the effects of using different diagnostic systems in clinical trials, and discusses factors affecting the design and interpretation of such trials. The book also reviews the effect of social and environmental factors on the course of schizophrenia, which are often overlooked. Available rating scales for assessment of clinical state and social functioning in schizophrenia are appraised, and there is a complete and up-to-date review of both conventional and more experimental treatments for schizophrenia. Lastly, there is an exhaustive review of the side-effects of neuroleptics, their pathogenesis and treatment, and a detailed examination of what is known about extrapyramidal disorders and tardive dyskinesia.

Table of Contents

  • R Rodnight: Peripheral biochemistry in schizophrenia
  • P B Bradley: Pharmacology of antipsychotic drugs
  • S D Iversen: Animal models of schizophrenia
  • S H Curry: Applied clinical pharmacology of schizophrenia
  • B Costall & R J Naylor: Neurotransmitter hypothesis of schizophrenia
  • I Brockington: Diagnosis of schizophrenia and schizoaffective psychoses
  • S R Hirsch: Influence of social experience and environment on the course of schizophrenia
  • S R Hirsch & K D Macrae: Essential elements in the design of clinical trials
  • R Manchanda & S R Hirsch: Rating scales for clinical studies on schizophrenia
  • S Platt: Evaluating social functioning. A critical review of scales and their underlying concepts
  • S R Hirsch: Clinical treatment of schizophrenia
  • C D Marsden, R H S Mindham & A V P MacKay: Extrapyramidal movement disorders produced by antipsychotic drugs
  • J G Edwards: The untoward effects of antipsychotic drugs: pathogenesis and management
  • Index.

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