Advances in drug delivery systems, 4 : proceedings of the Fourth International Symposium on Recent Advances in Drug Delivery Systems, SaltLake City, UT, U.S.A., February 21-24, 1989
著者
書誌事項
Advances in drug delivery systems, 4 : proceedings of the Fourth International Symposium on Recent Advances in Drug Delivery Systems, SaltLake City, UT, U.S.A., February 21-24, 1989
Elsevier, 1990
大学図書館所蔵 全2件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
"This set of papers has been published as a special issue of Journal of controlled release, vol. 11, issues 1-3."
Includes bibliographical references and indexes
内容説明・目次
内容説明
This symposium provided a setting in which scientists could gather to discuss recent advances and state-of-the-art technology in drug delivery. Speakers included pharmaceutical scientists, polymer chemists, bioengineers, pharmacologists and physicians who were considered to be leaders in the field of research and development of drug delivery systems. Perspectives on drug delivery systems and development have changed markedly since the first symposium on this subject was held. Focus on biological mechanisms and interactions important to drug delivery systems has increased. This changing emphasis is reflected in the five major topics discussed: transport mechanisms across membranes, proteins and macromolecular drug delivery, new developments in drug delivery, pharmacokinetics and pharmacodynamics in controlled drug delivery, and targeting and site-specific delivery. The breadth of topics covered illustrates the interdisciplinary and multifaceted nature of drug delivery systems.
目次
I. Transport Mechanisms Across Membranes. Biophysical model approaches to mechanistic transepithelial studies of peptides (N.F.H. Ho et al.). Transport and permeability properties of human Caco-2 cells: An in vitro model of the intestinal epithelial cell barrier (G. Wilson et al.). Nutrient effects on intestinal drug absorption (D. Fleisher et al.). Blood-brain barrier: Mechanisms of peptide regulation and transport (K.L. Audus). Delivery of vital drugs to the brain for the treatment of brain tumors (N.H. Greig et al.). Mechanisms and facilitation of corneal drug penetration (V.H.L. Lee). II. Transdermal and Iontophoretic Delivery. Solvent-mediated alterations of the stratum corneum (K. Knutson et al.). Electrochemical and iontophoretic studies of human skin (J.D. DeNuzzio, B. Berner). A comparison of pulsed and continuous current iontophoresis (T. Baniefski, R.R. Burnette). In vitro and in vivo evaluation of transdermal iontophoretic delivery of hydromorphone (R.V. Padmanabhan et al.). III. Proteins and Macromolecular Drug Delivery. The clinical efficacy of poly(ethylene glycol)-modified proteins (F. Fuertges, A. Abuchowski). Alteration of biopharmaceutical properties of drugs by their conjugation with water-soluble macromolecules: Uricase-dextran conjugate (T. Fujita et al.). Cell delivery and tissue regeneration (A.I. Caplan). Albumin-heparin microspheres as carriers for cytostatic agents (H.F.M. Cremers et al.). Mechanochemical approaches to self-regulating insulin pump design (R.A. Siegel, B.A. Firestone). Self-regulated glycosylated insulin delivery (S.W. Kim et al.). IV. Microspheres, Liposomes and Other Delivery Systems. Controlled vaccine release in the gut-associated lymphoid tissues. I. Orally administered biodegradable microspheres target the Peyer's patches (J.H. Eldridge et al.). Preparation and permeability characteristics of microcapsule membranes (T. Kondo). Liposomes as a delivery system for membrane-active antitumor drugs (R.L. Juliano, S.S. Daoud). Drug-laden liposomes in antitumor therapy and in the treatment of parasitic diseases (D.J.A. Crommelin et al.). Controlled release implants for cardiovascular disease (R.J. Levy et al.). Thermally on-off switching polymers for drug permeation and release (T. Okano et al.). V. Targeting and Site-specific Delivery. Polymer micelles as novel drug carrier: Adriamycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer (M. Yokoyama et al.). The potential of water-soluble polymeric carriers in targeted and site-specific drug delivery (J. Kopecek). Peptide sequences that target proteins for lysosomal degradation (J.F. Dice). Antibody-linked chelating polymers for immunoimaging in vivo (V.P. Torchilin et al.). VI. Pharmacokinetics and Pharmacodynamics. A structured approach to the development of a controlled-release drug delivery system for a b-adrenoceptor blocking drug (V.A. John).
「Nielsen BookData」 より