Cellular and molecular targets for chemoprevention
著者
書誌事項
Cellular and molecular targets for chemoprevention
CRC Press, c1992
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Cellular and Molecular Targets for Chemoprevention provides comprehensive coverage of target mechanisms that have proved valuable in chemoprevention research, in addition to mechanisms that may prove valuable in the near future. The book discusses such topics as growth factor receptor modulation, cell-to-cell communication, differentiation modulation, antisense olgonucleotides, tumor suppressor genes, free radical scavengers, and polyamine synthesis inhibition.
Cellular and Molecular Targets for Chemoprevention will be welcomed by scientists in all areas of cancer/chemoprevention research, pharmaceutical researchers, and advanced students.
目次
CELL MEMBRANE MODIFICATIONS. Growth Factor Therapy: Potential Uses of Transforming Growth Factor Betas (Larry E. Gentry). Membrane Lipids and Signaling in Cell Growth Regulation (Curtis L. Ashendel). Induction of Gap Junctional Communication by Retinoids and Carotinoids: Proposed Role in Cancer Chemoprevention (John S. Bertram). NUCLEAR TARGETS OF CHEMOPREVENTION. Regulation of Human DNA Repair Gene Expression (Michael A. Sirover). Antisense Oligonucleotides (Stanley T. Crooke). Effects of All-Trans Retinoic Acid on Growth, Differentiation and Oncogene Expression (Dharam P. Chopra). Zn-Fingers as Potential Targets for Chemoprevention (F. William Sunderman). Tumor Suppression in a Human Colorectal Carcinoma Cell Line (Michele Goyette). Chemical Inhibitors of Polycyclic Aromatic Hydrocarbon Mutagenesis and Carcinogenesis: Ellagic Acid Analogues (P. David Josephy). CYTOPLASMIC TARGETS. Potential Strategies of Chemoprevention Through Modulation of Protein Kinase C Activity (Catherine A. O'Brian). Free Radicals as Targets for Cancer Chemoprevention (Thomas W. Kensler). Role of Phase II Enzyme Induction in Chemoprotection Against Cancer (Paul Talalay). Ornithine Decarboxylase, A Possible Target for Human Cancer Prevention (Ajit K. Verma). Arachidonic Acid Metabolism (Terry V. Zenser). Chemoprevention by Inhibition of Carcinogen-DNA Adduct Formation (Gary D. Stoner). Cytoskeletal Modifications and Aneuploidy: Mapping DNA/Protein Domains in the Centromere (Bill R. Brinkley). Calcium, Driver of Cell Cycles, Trigger of Differentiation, and Killer of Cells (James F. Whitfield). Immunomodulation of Carcinogenesis (Stuart Sell). Modulation of Cell Invasion by Retinoids (Reuben Lotan).
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