T-cell-directed immunointervention

書誌事項

T-cell-directed immunointervention

edited by Jean-François Bach

(Frontiers in pharmacology & therapeutics)

Blackwell Scientific Publications, 1993

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Autoimmunity, the phenomenon by which the body's immune system attacks itself instead of invading organisms, is a factor in a wide range of currently

目次

  • Part 1 - Cyclosporin:
  • Cellular mode of action of cyclosporin A
  • Immunological effects of cyclosporin
  • Pharmacokinetics, drug interactions and analytical measurement of cyclosporin
  • The use of cyclosporin in organ transplantation
  • The use of cyclosporin in autoimmune diseases
  • Part 2 - FK 506:
  • Pharmacology and molecular action
  • Overview of FK 506 in transplantation
  • Part 3 - Anti T cell monoclonal antibodies:
  • Anti-CD3 and anti-TCR monoclonal antibodies
  • Therapeutic anti-CD4 antibodies
  • Anti-T cell receptor VBeta antibodies for treatment of autoimmune diseases
  • Interleukin-2 receptor-directed immunosuppressive therapies: antibody or cytokine based targetting molecules
  • Part 4 - Other approaches:
  • Towards idiotype specific therapy in autoimmune disease
  • Anti-MHC class II antibodies
  • Use of MHC antagonists to prevent and treat autoimmune disease in animal models

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