Biological performance of materials : fundamentals of biocompatibility
著者
書誌事項
Biological performance of materials : fundamentals of biocompatibility
Dekker, c1992
2nd ed
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
The second edition of this text and reference contains: a chapter on the design and selection of biomaterials for specific applications; new data on drug release as an example of leaching, as well as the effects of surface treatment of biomaterials and surface succession of serum proteins; additional details on mechanical degradation of composite materials, and the mechanisms and kinetics of absorbable materials; recent information on the complement system and relative contributions of chemical, mechanical and electrical factors to local host response; current legal and regulatory developments, such as the Safe Medical Device Act (1990); a new section on mechanisms of metal management in vivo and on chromium metabolism; and chapters on properties of widely-used biomaterials, and on recognizing clinical symptoms referable to biomaterials.
目次
- Part 1 General considerations: biocompatability - definitions and issues
- introduction to the biological environment. Part 2 Material response - function and degradation of materials in vivo: swelling and leaching
- corrosion and dissolution
- reactions of biological molecules with biomaterial surfaces
- mechanics of materials - deformation and failure
- friction and wear
- implant materials - properties. Part 3 Host response - biological effects of implants: the inflammatory process
- coagulation and haemolysis
- adaptation
- allergic foreign-body response
- chemical and foreign-body carcinogenesis
- mineral metabolism
- systemic distribution and excretion
- effects of degradation products on remote organ functions
- diagnosis of host response. Part 4 Methods of test for biological performance: in vitro test methods
- in vivo implant models
- qualification of implant materials
- standardization and regulation of implant materials
- design and selection of implant materials.
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