Tumor necrosis factor : structure-function relationship and clinical application
著者
書誌事項
Tumor necrosis factor : structure-function relationship and clinical application
Karger, 1992
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注記
"3rd International Conference on Tumor Necrosis Factor and Related Cytokines, Makuhari, Chiba, November 21-25, 1990."
Includes bibliographical references and index
内容説明・目次
内容説明
Tumour necrosis factor (TNF) can no longer be regarded solely as a tumour cytotoxic or cytostatic agent, but is now recognized as exerting a multitude of effects on many different cell types. This volume surveys recent advances in the field of TNF and related cytokines. The main topics are areas that relate to structure-function relationship; advances in the molecular characterization of TNF receptors; the role of TNF in infectious and non-infectious diseases; TNF's role in the development and differentiation of various tissues; clinical application of TNF in diagnosis and therapy, and TNF and inhibitors in infectious diseases, autoimmune diseases and cancer.
目次
- Biochemical and molecular characterization of TNF receptors/TNF-like receptors
- TNF-mediated cytotoxicity - mechanism and regulation
- role of TNF in maturation and differentiation
- role of TNF-alpha in tumour cell destruction
- role of TNF in the pathogenesis of diseases
- clinical applications.
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