Pharmaceutical skin penetration enhancement
著者
書誌事項
Pharmaceutical skin penetration enhancement
（Drugs and the pharmaceutical sciences, v. 59）
M. Dekker, c1993
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
This reference work - written by more than 35 leading international experts in the field of percutaneous penetration - fully explains the mechanisms and means of enhanced skin absorption in drug therapy.;The book identifies the features that an enhancer should possess for maximum activity and addresses underlying physico-chemical factors of the penetrant that affect the drug absorption process.;Pharmaceutical Skin Penetration Enhancement introduces all techniques used for basic research into skin penetration enhancement; reviews the advantages and limitations of various chemical enhancers; compares the use of physical enhancement during the processes in iontophoresis; and more.;Containing over 180 drawings, photographs, micrographs, and tables, and providing nearly 1000 bibliographic references, Pharmaceutical Skin Penetration Enhancement is a practical resource for both investigators conducting fundamental research in the field and for those working in an industrial setting, including pharmaceutical scientists, dermatologists, toxicologists, and cosmetic chemists, and upper-level undergraduate and graduate students in these disciplines.
目次
- Water - the most natural penetration enhancer, Michael S. Roberts and Michael Walker
- simple alkyl esters as skin penetration enhancers, David R. Friend and Jorge Heller
- phospholipids as skin penetration enhancers, Gary P. Martin
- terpenes as skin penetration enhancers, Brian W. Barry and Adrian C. Williams
- mechanisms and prediction of nonionic surfactant effects on skin permeability, Edward J. French et al
- interaction between anionic surfactants and skin, J. Gordon Black
- in vitro analysis of QSAR in wanted and unwanted effects of azacycloheptanonesas transdermal penetration enhancers, Harry E. Bodde et al
- oleyl surfactants as skin penetration enhancers - skin irritation and in vitro toxicity to cultured human skin cells, Harry E. Bodde et al
- synergistic effects in percutaneous enhancement, Birgitte Mollgaard
- supersaturated solutions as topical drug delivery systems, Adrian F. Davis and Jonathan Hadgraft
- infrared spectroscopy of stratum corneum lipids - in vitro results and their relevance to permeability, Russell O. Potts and Michael L. Francoeur
- the use of ultrasound in skin penetration enhancement, James C. McElnay et al
- iontophoretic drug delivery, Philip G. Green et al
- technological aspects of penetration enhancers in transdermal systems, Thomas Hille
- veterinary applications of skin penetration enhancers, Kenneth A. Walters and Michael S. Roberts
- hydrotropy and penetration enhancement, Anthony J.I. Ward and David W. Osborne
- molecular modelling of skin permeation enhancement by chemical agents, Keith R. Brain and Kenneth A. Walters
- skin penetration enhancement - clinical pharmacological and regulatory considerations, Vinod P. Shaah et al.
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