Bioactive natural products

著者

• Rahman, Atta-ur-
• Basha, Fatima Z.

書誌事項

Bioactive natural products

edited by Atta-ur-Rahman, Fatima Z. Basha

（Studies in natural products chemistry / edited by Atta-ur-Rahman, v. 13, 21-30, 32-38, 47-50, 52-64）

Elsevier, 1993-

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• pt. N
• pt. O
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• [v. 62]
• [v. 63]
• v. 64

注記

[Vol. 61-62]: Title from spine

Editor: v. 22-30, 33-38, 47-50, 52-64. Atta-ur-Rahman

Includes bibliographies and indexes

内容説明・目次

巻冊次

pt. F ISBN 9780080440019

内容説明

Natural products play an integral and ongoing role in promoting numerous aspects of scientific advancement, and many aspects of basic research programs are intimately related to natural products. The significance, therefore, of the Studies in Natural Product Chemistry series, edited by Professor Atta-ur-Rahman, cannot be overestimated. This volume, in accordance with previous volumes, presents us with cutting-edge contributions of great importance.

目次

• Acid-catalyzed epimerization of bioactive indole alkaloids and their derivatives, M. Berner et al
• Antitumor-promoting and anti-inflammatory activities of triterpenoids and sterols from plants and fungi, T. Akihisa, K. Yasukawa
• Bioactive oleanene glucuronides obtained from fabaceous plants, J. Kinjo, T. Nohara
• Biotransformation of terpenoids by micro-organisms, Jan C.R. Demyttenaere
• Cycloartane and oleanane saponins from Astragalus sp, L. Verotta, N.A. El-Sebakhy
• Labdane-type diterpenes - chemistry and biological activity, C. Demetzos, K.S. Dimas
• Metabolism of the tomato saponin-tomatine by phytopathogenic fungi, M. Ruiz-Rubio et al
• Heme aggregation inhibitors - antimalarial drugs targeting an essential biomineralization process, J. Ziegler et al
• Bioactive peptides as signal molecules in plant defense, growth and development, A. Schaller
• Enzymes involved in the biosynthesis of brassinosteroids, J. Winter
• Immunopotentiating effects of a glycoprotein from Chlorella vulgaris strain CK and its characteristics, K. Tanaka et al
• Hepatoprotective effect of plant components: Inhibition of tumor necrosis Factor-dependent inflammatory liver injury, K. Hase et al
• Induction and regulation of biosynthetic activity of phytoalexin in carrot cells, F. Kurosaki
• Inhibition of eukaryote signal transduction components by plant defensive secondary metabolites, G.M. Polya
• Flavonoids and cardiovascular diseases, J. Duarte et al. (Part contents).

巻冊次

[v. 63] ISBN 9780128179017

内容説明

Studies in Natural Products Chemistry, Volume 63, covers the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques that have made it possible to rapidly isolate and determine the structures and biological activity of natural products. The book highlights these new and exciting opportunities in the field of new drug development to the pharmaceutical industry. As natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects, this book is an ideal resource on the material presented.

目次

1. Recent Advances in the Licorice Root Constituent Dibenzoylmethane as A Potential Therapeutic Option for Cancer 2. Polyphenols for Skin Cancer: Chemical Properties, Structure-Related Mechanisms of Action and New Delivery Systems 3. The Leucetta Alkaloids: Synthetic Aspects 4. Metal-catalyzed, Bidentate Directing Group-assisted C-H Functionalization: Application to the synthesis of Complex Natural Products 6. Antioxidant, Anti-Inflammatory and Anticancer Potential of Natural Bioactive Compounds from Seaweeds 7. Comparison of the Ginsenoside Composition of Asian Ginseng (Panax ginseng) and American Ginseng (Panax quinquefolius L.) and their Transformation Pathways 8. Use of Natural Products in the Prevention and Management of Type 2 Diabetes 9. In vitro Fucoxanthin Production by the Phaeodactylum Tricornutum Diatom 10. Neuroprotective Potential of Phytochemicals via in silico Molecular Docking Techniques 11. Isolation and Structure Elucidation of Bioactive Polyphenols 12. Curcumin and Molecular Targets in Eye Diseases 13. Phytochemistry and Biological Activities of Algerian Centaurea and Related Genera 14. Phytoconstituent Plumbagin: Chemical, Biotechnological and Pharmaceutical Aspects 15. Advances in the Synthesis of Furo[2,3-b]Furanone-containing Natural Products 16. Advances in Dammarane-type Triterpenoid Saponins from Bacopa Monnieri: Structure, Bioactivity, Biotechnology and Neuroprotection

巻冊次

v. 64 ISBN 9780128179031

内容説明

Studies in Natural Products Chemistry, Volume 64, covers the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques that have made it possible to rapidly isolate and determine the structures and biological activity of natural products. The book highlights these new and exciting opportunities in the field of new drug development to the pharmaceutical industry. As natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects, this book is an ideal resource on the material presented.

目次

1. The C-19 Methyl Substituted Sarpagine-Macroline-Ajmaline Alkaloids: Diversity, Occurrence, Bioactivity, and Synthesis 2. Recent Progress in the Synthesis of Antimalarial Indoloquinoline Natural Products and Analogues 3. Anticancer Activity of Natural Coumarins for Biological Targets 4. Silymarin Compounds: Chemistry, Innovative Extraction Techniques and Synthesis 5. The Olive-Tree Leaves as a Source of High-Added Value Molecules: Oleuropein 6. Progress in Studies on Meroterpenoids 7. Effects of Dietary N-3 Polyunsaturated Fatty Acids on Cardiovascular Disease 8. Potential of Natural Bioactive C-glycosyl Flavones for Antidiabetic Properties 9. Natural Products Encompassing Anti Tuberculosis Activities 10. Physiological Effects of Carotenoids on Hyperglycemia and Associated Events 11. Pharmacophore Modeling and Virtual Screening for the Discovery of Biologically Active Natural Products 12. Formation of Three-Dimensional Polymer Structures through Radical and Ionic Reactions of Peroxychitosan 13. Bioactive Natural Products as Potent Inhibitors of Xanthine Oxidase 14. Organocatalyzed a-Aminooxylation/Amination of Aldehydes and their Sequential Reactions: A Versatile Tool for the Synthesis of Bioactive Molecules 15. Bioactive Compounds of Streptomyces: Biosynthesis to Applications

巻冊次

pt. B ISBN 9780444504692

内容説明

Natural products play an integral and ongoing role in promoting numerous aspects of scientific advancement, and many aspects of basic research programs are intimately related to natural products. The significance, therefore, of the Studies in Natural Product Chemistry series, edited by Professor Atta-ur-Rahman, cannot be overestimated. This volume, in accordance with previous volumes, presents us with cutting-edge contributions of great importance.

巻冊次

pt. C ISBN 9780444505880

内容説明

Natural products play an integral and ongoing role in promoting numerous aspects of scientific advancement, and many aspects of basic research programs are intimately related to natural products. The significance, therefore, of the Studies in Natural Product Chemistry series, edited by Professor Atta-ur-Rahman, cannot be overestimated. This volume, in accordance with previous volumes, presents us with cutting-edge contributions of great importance.

目次

• The metabolism and biochemical actions of aklaloids in animals, (T. Robinson)
• Using chemical ecology to locate new antifungal natural products, (S.J. Eckerman et al.)
• Natural triterpenoids as anti-inflammatory agents, (J.L. Rios et al.)
• Current status of the chemistry and synthesis of natural antimalarial compounds and natural substances used to alleviate symptoms of diabetes (aldose reductase and A-glucosidase inhibitors), (K. Kawanishi, N.R. Farnsworth)
• A diradical route to bioactive natural products and their analogues, (R.D. Little, M.M. Ott)
• Bioactive fungal natural products through classic and biocombinatorial approaches, (Z.-D. Jiang, Z. An)
• The chemistry of 2-aminocyclopentanecarboxylic acid, (F. Fulop)
• Structure-activity relationship of flavonoids as antioxidant and pro-oxidant compounds, (P. Cos et al.)
• Recent advances in the search for antioxidant activity in South American plants, (C. Desmarchelier et al.)
• Insect juvenile hormones in plants, (J.C. Bede, S.S. Tobe)
• Antiulcer and gastroprotective activity of flavonic compounds - mechanisms involved, (M.J. Martin et al.)
• Simple flavones possessing complex biological activity, (S. Tahara, J.L. Ingham)
• Medicinal plants with anticonvulsant activities, (M. Raza et al.)
• Chemistry, structure and biological activity of anthracenones of the Karwinskia genus, (A. Pieyro-Lopez, N. Waksman)
• Bioactive natural products derived from Polygonum species of plants: their structure and mechanisms of action, (N. Ogwuru, M. Adamczeski)
• Hypericum perforatum - St. John's Wort - chemical, pharmacological and clinical aspects, (C.A.J. Erdelmeier et al.)
• Tropane alkaloids: old drugs used in modern medicine (P. Christen).

巻冊次

pt. D ISBN 9780444506061

内容説明

Natural products play an integral and ongoing role in promoting numerous aspects of scientific advancement, and many aspects of basic research programs are intimately related to natural products. The significance, therefore, of the Studies in Natural Product Chemistry series, edited by Professor Atta-ur-Rahman, cannot be overestimated. This volume, in accordance with previous volumes, presents us with cutting-edge contributions of great importance.

目次

• Microbial models of mammalian metabolism, Sampangines, (K.Y. Orabi)
• Ansamycin antibiotics discovery, classification, biosynthesis and biological activities, (S. Funayama, G.A. Cordell). (1-3, 1-6)-B-D-Glucans of yeasts and fungi and their biological activity, (G. Kogan)
• Organic chemistry and biological activity of metabolites derived from marine sea plumes, pseudopterogorgia species of gorgonian octacorals, (E. Katz, M. Adamczeski)
• Bioactive secondary metabolites from Okinawan sponges and tunicates, (J. Kobayashi, M. Ishibashi)
• Aromatic alkaloids from ascidians, (B.F. Bowden)
• Bioactive quassinoids, (M. Okano, N. Fukamiya, K.H. Lee)
• Coumarins, the bioactive structures with antifungal property, (S. Sardari, S. Nishibe, M. Daneshtalab)
• Chemical and biological perspectives of ellagitannin oligomers from medicinal plants, (T. Yoshida, T. Hatano, H. Ito, T. Okuda)
• Recent studies on the chemistry and biological activities of the organosulfur compounds of garlic (Allinum sativum), (A. Kamel, M. Saleh)
• Chemistry of some natural products of biological interest, (S.M. Mahato)
• Bioactive constituents of the family Dipterocarpaceae, (E. Seo, A.D. Kinghorn).
• The veratrum alkaloids: natural tools for studying embryonic development, (W. Gaffield)
• Chemical and biological evaluation of genus Teucrium, (A. Ulubelen, G. Topcu, U. Sonmez)
• Ethnobotanical used of celastracae, Bioactive metabolites, (A.G. Gonzalez, I.L. Bazzocchi, L. Moujir, I.A. Jimenez)
• Antioxidant phenolic metabolites from fruit and vegetables and changes during postharvest storage and processing, (F.A. Tomas-Barberan, F. Ferreres, M.I. Gil)
• Phytochemistry of the Zingiberaceae, (O. Pancharoen, U. Prawat, P. Tuntiwachwuttikul).

巻冊次

pt. E ISBN 9780444506436

内容説明

Natural products play an integral and ongoing role in promoting numerous aspects of scientific advancement, and many aspects of basic research programs are intimately related to natural products. The significance, therefore, of the Studies in Natural Product Chemistry series, edited by Professor Atta-ur-Rahman, cannot be overestimated. This volume, in accordance with previous volumes, presents us with cutting-edge contributions of great importance.

目次

• Total syntheses of (+)-eremantholide A and (-)-verrucarol - from D-glucose to biologically intriguing sesquiterpenes, (K. Takao et al.)
• The synthesis of bioactive sesquiterpenes from santonin, (G. Blay et al.)
• Structure/function relationships of immunostimulating saponins, (J.B. Press et al.)
• Synthesis of bioactive terpenes from Wieland-Miescher ketone and its methyl analog, (A.K. Banerjee, M. Laya-Mimo)
• Anti-tumor-promoting activities (cancer chemopreventive activities) of natural products, (K. Takao, M. Takasaki)
• Antitumor compounds isolated from higher plants, (H. Itokawa et al.)
• Medical aspects of some steroidal natural products, (N.S. Bhacca)
• Farnesyl-protein transferase - a new paradigm for cancer chemotherapy, advances in discovery and development of natural product inhibitors, (R.B. Lingham, S.B. Singh)
• Natural products as antiviral agents, (K.A. El Sayed)
• Polycyclic amine alkaloids (3-alkylpiperidine alkaloids) - novel marine bioactive compounds - structure, synthesis and biochemical aspects, (J. Rodr guez)
• Unsaturated amides from Piper species, (Piperaceae) (G.M. Strunz)
• Recent advances in the chemistry of lignans, (R.S. Ward)
• Bioactive compounds from selected plants used in the 16th century Mexican traditional medicine, (E. B jar et al.)
• A brief summary of biologically active compounds from Magnolia spp, (M.A. Kelm, M.G. Nair)
• Analysis of chemical-structure-activity relationships to identify new pro-drugs with unique mechanisms of actions in Kampo medicines and other natural products, (I. Kimura et al.)
• Bioactive compounds from four endophytic Penicillium sp. of a northwest Pacific yew tree, (A.A. Stierle, D.B. Stierle)
• Marine fungal substances, (J.-F. Verbist et al.)
• Natural product-derived treatments of neuropsychiatric disorders - review of progress and recommendations, (J. Lake).

巻冊次

pt. G ISBN 9780444510044

内容説明

Volume 26 of "Studies in Natural Product Chemistry" presents the chemistry of a large number of exciting natural products. All of the chapters reflect the importance of the biological activity of nature's molecules - activity which continues to inspire the evolution of new drugs against disease. Topics covered include: the triterpenoid saponins from the Caryophyllaceae family; developments in the total synthesis of bioactive marine fatty acids; and the chemistry and biological activity of secologanin, lignans, saffron and the bark of Fraxunus ornus. A range of natural compounds which are utilised in the assessment of environmental issues are also discussed, as are the pharmacological activities and applications of essential oils, plant growth regulators and phytotoxins. The chemistry and bioactivity of secondary metabolites is reviewed in this volume, together with the structure, chemistry and biological activity of resveratrol oligomers. Recent developments in the chemical behaviour, toxicology and chemical ecology of compounds found in bracken fern are reviewed. The occurrence, structure and bioactivity of 1,7-diarylheptanoids is covered, together with the structures and biological activities of natural insecticides. Potential anti-parasitic substance from natural sources is presented here, as is the chemistry and bioactivity of nitric oxide (NO) in plant and animal cells. The role of O-aminophenol-type tryptophan metabolites in living organisms is also discussed.

目次

• Triterpenoid saponins from caryophyllaceae family, (Zhonghua Jia et al)
• Recent developments in the total synthesis of bioactive marine fatty acids, (N.M. Carballeira)
• Some aspects of the chemistry of secologanin, (L.F. Szabo)
• The lignans of Podophyllum, (R.M. Moraes)
• New findings on the bioactivity of lignans, (J.L. R os et al)
• Crocus sativus-biological active constituents, (M. Liakopoulou-Kyriakides, D.A. Kyriakidis)
• Chemical components of Fraxinus ornus bark-structure and biological activity, (I.N. Kostova, T. Iossifova)
• Natural compounds for the management of undesirable freshwater phytoplankton blooms, (K.K. Schrader et al)
• Pharmacological activities and applications of Salvia sclarea and Salvia desoleana essential oils, (A.T. Peana, M.D.L. Moretti)
• Secondary metabolites with antinematodal activity, (E.L. Ghisalberti)
• Resveratrol oligomers - structure, chemistry, and biological activity (R.H. Cichewicz, S.A. Kouzi). (Part contents).

巻冊次

pt. H ISBN 9780444512307

内容説明

Natural products play an integral and ongoing role in promoting numerous aspects of scientific advancement, and many aspects of basic research programs are intimately related to natural products. The significance, therefore, of the 28th volume in the Studies in Natural Product Chemistry series, edited by Professor Atta-ur-Rahman, cannot be overestimated. This volume, in accordance with previous volumes, presents us with cutting-edge contributions of great importance. The first paper presents over 100 compounds obtained from Broussonetia spp., and discusses biological activities. This is followed by similar contributions dealing with the genus Licania and Ginkgo biloba. Additional papers describe in detail a number of interesting and important natural compounds or structural classes: retinoids, tetramic acid metabolites, isoprenylated flavonoids, plant polyphenols, crocin, marcfortine and paraherquamide, acaricides, podolactones, triterpene glycosides and sulfur-containing marine compounds. An additional paper focuses on the antitumor activities of lipids, and a final contribution deals with natural product amelioration of cancer chemotherapy-induced adverse reactions.

目次

• Sweet-tasting and sweetness modifying constituents of plants, N.C. Kim, A. Douglas Kinghorn
• Chemical responses to plant injury and plant ageing, G. Spiteller
• Neuraminic acid and its structures, chemistry, biological activity, A. Bianco, C. Melchioni
• Some aspects of the chemistry of quaternary benzo[c]phenanthridine alkaloids, J. Dorstal, J. Slavik
• Benzoxazinones in plants - occurence, synthetic access, and biological activity, D. Sicker, M. Schultz
• Indolizidine and quinolizidine alkaloids structure and bioactivity, A.M. Lourenco et al.
• Safety evaluation of Stevia and stevioside, J.M.C. Geuns
• Abscisc acid analogs for probing the mechanism of abscisic acid reception and inactivation, Y. Todoroki, N. Hirai
• Chiral monoterpenoids in plants-enantioselective chromatographic analysis, and their bioactivity, M. Asztemborska, J. Renata Ochocka
• Biochemical and pharmacological studies of natural products isolated from various medicinal plants and foodstuffs, Y. Kimura, H. Okuda
• Secondary metabolites of genus Astragalus - structure and biological activity, L. Pistelli
• Chemical characterization and biological activities of the genus Tanacetum, Compositae
• , N. Gohren et al.
• Bioactive components of Bupleurum rigidum L. Sub sp. rigidum, S. Sanchez Contreras et al.
• Minor polar compounds of olive oil - composition, factors of variability and bioactivity, M. Dell'agli, E. Bosisio
• Plant peroxidases
• versatile catalysts in the synthesis of bioactive natural products, A. Ros Barcelo, F. Pomar
• Naturally occuring oligopeptides with more than one biological actvities, M. Liakopoulou-Kyriakdes
• Modulation of protein phosphorylation by natural products, S. Manez, M. Del Carmen Recio
• Cytotoxicity of flavonoids of cancer cell lines. Structure-activity relationship, M. Lopez-Lazaro et al.

巻冊次

pt. I ISBN 9780444514158

内容説明

Studies in Natural Products Chemistry: Bioactive Natural Products (Part I) contains articles written by leading authorities in their respective fields of research. It presents current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products.

目次

Bioactive compounds from the genus Broussonetia Chemical and biological studies on Licania genus Recent progress in retinoid chemistry Bioactive tetramic acid metabolites Chemistry and biological activities of Ginkgo biloba Chemistry and biological activities of isoprenylated flavonoids from medicinal plants Plant polyphenols: Structure, occurrence and bioactivity Promising pharmacological actions of crocin in Crocus sativus on the central nervous system Synthesis and modification of marcfortine and paraherquamide class of anthelmintics Acaricides of natural origin, personal experiences and review of literature (1990-2001) Podolactones: A group of biologically active norditerpenoids Antitumoral activity of lipids A studies in animal models and cancer patients Prevention of cancer chemotherapy drug-induced adverse reaction, antitumor and antimetastatic activities by natural products Biologically active triterpene glycosides from sea cucumbers (holothuroidea, echinodermata) Sulfur-containing natural products from marine invertebrates

巻冊次

pt. J ISBN 9780444515100

内容説明

Natural products play an integral and ongoing role in promoting numerous aspects of scientific advancement, and many aspects of basic research programs are intimately related to natural products. The significance, therefore, of the 29th volume in the Studies in Natural Product Chemistry series, edited by Professor Atta-ur-Rahman, cannot be overestimated. This volume, in accordance with previous volumes, presents us with cutting-edge contributions of great importance.

目次

Ecdysteroid Structure-Activity Relationships Potentially Cancer Chemopreventive and Anti-Inflammatory Terpenoids from Natural Sources Total Synthesis of Biologically Intriguing Drimane-Type Sesquiterpenoids Via Intramolecular Diels-Alder Approaches Synthesis of Bioactive Diterpenes Search for Bioactive Natural Products from Unexploited Microbial Resources Polyhydroxy-p-Terphenyls and Related p-Terphenylquinones from Fungi: Overview and Biological Properties Halogen-Containing Antibiotics from Streptomycetes Natural Bridged Biaryls with Axial Chirality and Antimitotic Properties Synthetic Studies on Biologically Active Alkaloids Starting from Lactam-Type Chiral Building Blocks Advances in Chemical Synthesis of Carbasugars and Analogues The Biosynthesis and Properties of Anti-Carbohydrate Antibodies Protein and Non-Protein Protease Inhibitors from Plants Generating and Screening A Natural Product Library for Cyclooxygenase and Lipoxygenase Dual Inhibitors The Chemistry and Biology of Lapachol and Related Natural Products a and b-Lapachones

巻冊次

pt. K ISBN 9780444518545

内容説明

Many aspects of basic research programmes are intimately related to natural products. With articles written by leading authorities in their respective fields of research, Studies in Natural Products Chemistry, Volume 30 presents current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products. It is a valuable source for researchers and engineers working in natural product, and medicinal chemistry.

目次

Synthetic routes to discodermolide and pironetin: Two immunosuppressive and antitumoral. Antitumor and vascular physiological effects of natural products. Anti-obesity effects of natural products. Bioactive phenolic lipids. The use of natural products as sources of new analgesic drugs. Acid-treatment of arylpropanoid and arylethanoid derivatives-Access to natural and synthetic biologically active polyphenols. Labiatae flavonoids and their bioactivity. Biological activity of quinones. Serotonin (5-hydroxytryptamine) and the etiology of autism. Antiviral activities of polysaccharides from natural. Recent advances in the chemistry of bioactive 3-deoxy-ulosonic acids. Structure-activity relationships of naturally occurring active forms of vitamin D analogues. Charged carotenoid species. Bioactive constituents of the genus Hernandia. A survey on the hypericum genus: Secondary metabolites and bioactivity. Bioactive triterpenes and related compounds from celastraceae. Biologically active substances from the genus Baccharis L. (Compositae). Host defensive and pharmacological study of Chlorella vulgaris strain CK. Pharmacological activity of new , , receptor agonists and antagonists. Earthworm fibrinolytic enzyme.

巻冊次

pt. L ISBN 9780444521712

内容説明

Natural Product Chemistry continues to expand to exciting new frontiers of great importance in medicine. Written by international authorities in various fields of natural product chemistry, this latest volume in the well-established series Studies in Natural Products Chemistry contains 23 chapters, covering topics ranging from immunosuppressant and antimalarial compounds to bioactive substances useful in cancer and neural diseases. This present volume, will again be of great interest to research scientists and scholars working in the exciting field of new drug discovery.

目次

Synthesis of immunosuppressant FR901483 and biogenetically related TAN1251 alkaloids. Bioactive natural products from southern african marine invertebrates. Bioactive marine sesterterpenoids.Antimalarial lead compounds from marine organisms. Bioactive saponins with cancer related and immunomodulatory activity: Recent developments. Chemical and biological aspects of iridoid bearing plants of temperate region.Iridoids and secoiridoids from Oleaceae.Pharmacological activities of iridoids biosynthesized by route II.Chemistry and neurotrophic activity of seco-prezizaane- and anislactone-typesesquiterpenes from Illicium species. New insights into the bioactivity of cucurbitacins.Griseofulvin and other biologically active halogen containing compounds from fungi. Bioactive alkaloids of fungal origin. Chemistry and biological activities of naturally occurring phthalides.Chemistry and biological activity of polyisoprenylated benzophenone derivatives.The benzophenones: Isolation, structural elucidation and biological activities.Bioactive compounds from Tripterygium wilfordii.Bioactive natural compounds from medico-magic plants of bantu area.Bioactive non-alkaloidal constituents from the genus Erythrina.Chemical constituents and pharmacology of Aristolochia.Chemistry and bioactivity of withanolides from South American Solanaceae.Bioactive secondary metabolites related to life-cycle development of oomycete phytopathogens.Bioprospecting in the Berkeley PIT: Bioactive metabolites from acid mine waste extremophiles. Isoflavones as functional food components.

巻冊次

pt. M ISBN 9780444527172

内容説明

Natural products present in the plant and animal kingdom offer a huge diversity of chemical structures which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate, determine the structures and biological activity of natural products rapidly, thus opening up exciting new opportunities in the field of new drug development to the pharmaceutical industry.The present volume contains 22 articles written by leading experts in natural product chemistry on biologically active natural products. It includes research on a variety of different classes of natural products including sesquiterpenes, quassinoids, diterpenoids, lignans, oligostilbenes, phenylethanoids, phenylpropanoid glycosides, curcumin analogues, glycosphingolipids etc. Many of these have been found to be active in a number of different disease conditions.

目次

Foreword Preface Contributors Focus on fluorescent proteinsStructure, function and mode of action of select arthropod neuropeptidesNatural products as modulators of apoptosis and their role in inflammationSesquiterpenes classified as phytoalexinsBioactive triterpenes and related compounds from celastraceaeStructure-activity relationships of sesquiterpene lactonesSynthetic investigations in the field of drimane sesquiterpenoidsQuassinoids: Structure diversity, biological activity and synthetic studiesThe diterpenoids from the genus SideritisRecent developments in the asymmetric synthesis of lignansNatural oligostilbenesIsolation, structure elucidation and bioactivities of phenylethanoid glycosides from Cistanche, Forsythia and Plantago plantsPharmacological activities of phenylpropanoids glycosidesDevelopment of tubulin inhibitors as antimitotic agents for cancer therapyCholesterol biosynthesis inhibitors of microbial originStructure-activity relationships of curcumin and its analogs with different biological activitiesThe Vinca alkaloids: From biosynthesis and accumulation in plant cells, to uptake, activity and metabolism in animal cellsThe chemistry of Olea EuropaeaThe chemistry of the genus Cicer L.New research and development on the Formosan annonaceous plantsStructural and functional aspects of fungal glycosphingolipidsPhytochemical studies and pharmacological activities of plants in genus Hedyotis/OldeanlandiaSubject Index

巻冊次

pt. N ISBN 9780444531803

内容説明

This volume presents frontier reviews on recent developments on bioactive natural products in cutting-edge areas by eminent experts in their respective fields. Fourteen reviews treat diverse and different topics in natural products chemistry - basic ones, medicinally oriented ones, agro-oriented ones and ecologically oriented ones.It is an important addition to this important series on Natural Products Chemistry, generally acknowledged to be the leading series on this topic.

目次

Antitumor agent 248. Chemistry and antitumor activity of tylophorine-related alkaloidsLINYI WEI, ARNOLD BROSSI, SUSAN L. MORRIS-NATSCHKE, KENNETH F. BASTOW AND KUO-HSIUNG LEE Antitumor and antimetastatic actions of various natural productsYOSHIYUKI KIMURA Natural stilbenes and analogues as ntineoplastic agentsFULVIA ORSINI AND GUIDO SELLO Discoveries of the diels-alderasesAKITAMI ICHIHARA Lipids of membranes: Chemistry, biological role and applications as drug carriersSOPHIA HATZIANTONIOY AND COSTAS DEMETZOSMetabolism of plant hormones cytokinins and their function in signaling, celldifferentiation and plant developmentPETR GALUSZKA, LUKAS SPICHAL, DAVID KOPECNY,PETR TARKOWSKI, JITKA FREBORTOVA, MAREK SEBELA AND IVO FREBORT (+)-Biotin: A challenge for industrially viable total synthesis of natural productsMASAHIKO SEKI Biotechnology for the production of plant natural productsRAFAEL ZARATE, NABIL EL JABER-VAZDEKIS, ELENA CEQUIER-SANCHEZ, FATIMA GUTIERREZ-NICOLAS AND ANGEL G. RAVELORoles of insect and mammal pheromones: Vomeronasal receptorsDANIEL GARCIA VELAZQUEZ, JOSE J. MARRERO TELLADO AND ANGEL G. RAVELOStilbenoids: Chemistry and bioactivitiesKAI XIAO, HONG-JUN ZHANG, LI-JIANG XUAN, JUAN ZHANG,YA-MING XU AND DONG-LU BAI Tissue culture of medicinal plants: Micropropagation, transformation andproduction of useful secondary metabolitesKAYO YOSHIMATSU Isoquinuclidines: A review of chemical and pharmacological propertiesM.O. FARUK KHAN, MARK S. LEVI, C. RANDALL CLARK,SETH Y. ABLORDEPPEY, SAY-JONG LAW, NORMAN H. WILSON AND RONALD F. BORNE Hyaluronic acid: Its function and degradation in in vivo systemsGRIGORIJ KOGAN, LADISLAV SOLTES, ROBERT STERN,JUERGEN SCHILLER AND RANIERO MENDICHIHigh altitude plants, chemistry of acclimation and adaptationMIGUEL E. ALONSO-AMELOT

巻冊次

pt. O ISBN 9780444531810

内容説明

This volume presents frontier reviews of recent developments in bioactive natural products in cutting-edge areas by eminent experts in their respective fields. It is an essential addition to this important series on Natural Products Chemistry, generally acknowledged to be the leading series on this topic.

目次

R. DANIEL LITTLE AND GISELE A. NISHIGUCHI: Synthetic efforts toward, and biological activity of, thyrsiferol and structurally-related analogues KATSUHIRO UEDA AND DAISUKE UEMURA: Bioactive marine metabolites from okinawan watersMARIA JOSE ABAD MARTINEZ, LUIS MIGUEL BEDOYA DEL OLMO AND PAULINA BERMEJO BENITO: Natural marine antiviral productsVLADIMIR I. KALININ, DMITRY L. AMININ, SERGEY A. AVILOV, ALEXANDRA S. SILCHENKO AND VALENTIN A. STONIK: Triterpene glycosides from sea cucumbers (holothurioidea, echinodermata) XIAOHONG LIU, FANG XU, CHANGLUN SHAO, ZHIGANG SHE, YONGCHENG LIN AND WING LAI CHAN: Bioactive metabolites from marine microorganisms MARTA S. MAIER: Biological activities of sulfated glycosides from echinoderms TOM TURK, KRISTINA SEPEIC, INES MANCINI AND GRAZIANO GUELLA: 3-Aklypyridinium and 3-alkylpyridine compounds from marine sponges, their synthesis, biological activities, and potential useSHANTA S. BHAR AND M.M.V. RAMANA: Novel domino reactions for synthesis of bioactive diterpenoids and alkaloidsGAIL B. MAHADY, YUE HUANG, BRIAN J. DOYLE ANDTRACIE LOCKLEAR: Natural products as antibacterial agentsMARIA JOSE ABAD MARTINEZ, RUBEN MARTIN LAZARO,LUIS MIGUEL BEDOYA DEL OLMO AND PAULINA BERMEJO BENITO: Anti-infectious activity in the anthemideae tribeRAKESH MAURYA, GEETU SINGH AND PREM P. YADAV: Antiosteoporotic agents from natural sourcesELIANA RODRIGUES, RICARDO TABACH, JOSE CARLOS F. GALDUROZ AND GIUSEPPINA NEGRI: Plants with possible anxiolytic and/or hypnotic effects indicated by three Brazilian cultures - Indians, afro-Brazilians, and river-dwellersSIRLEI DAFFRE, PHILIPPE BULET, ALBERTO SPISNI, LAURENCE EHRET-SABATIER, ELAINE G. RODRIGUES ANDLUIZ R. TRAVASSOS: Bioactive natural peptidesHIDEKI HASHIZUME AND YOSHIO NISHIMURA: Cyclic lipopeptide antibiotics AHMED KABOUCHE AND ZAHIA KABOUCHE: Bioactive diterpenoids of Salvia species T. OEZANKA AND K. SIGLER: Biologically active compounds of semi-metals

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[v. 36] ISBN 9780444538369

内容説明

Natural products present in the plant and animal kingdom offer a huge diversity of chemical structures which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate, and then determine the structures and biological activity of natural products rapidly, thus opening up exciting new opportunities in the field of new drug development to the pharmaceutical industry. The series also covers the synthesis or testing and recording of the medicinal properties of natural products. "There is a good mix of chemistry, structure elucidation, synthesis, and biology in the various chapters, thereby appealing to a diverse readership. The diagrams are clear and the writing excellent. In summary, this is another excellent volume in a very valuable series on natural products for which Professor Atta-ur-Rahman is to be congratulated...... an important and essential asset for those libraries supporting the efforts of natural product research groups." Geoffrey A. Cordell, University of Illinois, Chicago, USA, PHYTOCHEMISTRY, Vol.65, 2004

目次

Preface 1. Isolation, Biological activities and Synthesis of the Natural Casuarines 2. The Acylpolyamines from Spider Venoms 3. Deep-Sea Hydrothermal Vents as a New Source of Drug Discovery 4. Marine Cyanobacteria: A Treasure Trove of Bioactive Secondary Metabolites for Drug Discovery 5. Novel Bioactive Peptides from Cyanobacteria: Functional, Biochemical and Biomedical Significance 6. Bioactive Marine Prenylated Quinones/Quinols 7. Chlorosulfolipids 8. Diversity and Ecological Significance of Fungal Endophyte Natural Products 9. Flavonoids as Anti-Inflammatory and Analgesic Drugs: Mechanisms of Action and Perspectives in the Development of Pharmaceutical Forms 10. Antileishmanial Natural Products from Plants Subject Index

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[v. 37] ISBN 9780444595140

内容説明

Natural products play an integral and ongoing role in promoting numerous aspects of scientific advancement, and many aspects of basic research programs are intimately related to natural products. With articles written by leading authorities in their respective fields of research, Studies in Natural Products Chemistry, Volume 37 presents current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products. It is a valuable source for researchers and engineers working in natural products and medicinal chemistry.

目次

Botanical Medicines for Diuresis: Cross-Cultural Comparisons The Artemisia L. Genus: a Review of Bioactive Sesquiterpene Lactones Secondary Metabolites with Antinematodal Activity from Higher Plants Beneficial Health Effects of Bioactive Compounds Present in Spices and Aromatic Herbs Bioactive Plant Isoprenoids: Biosynthetic and Biotechnological Approaches Trypanocidal Monoterpenes: Lead Compounds to Design Future Trypanocidal Drugs Plant and Fungi 3,4-Dihydroisocoumarins: Structures, Biological Activity and Taxonomic Relationships The Modern Analytical Determination of Botanicals and Similar Novel Natural Products by the HPTLC Fingerprint Approach Natural Antioxidants (NAO) of Plants Acting as Scavengers of Free Radicals Bioactive Natural Products as Potential Candidates to Control Aedes Aegypti, the Vector of Dengue Subject Index

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[v. 38] ISBN 9780444595300

内容説明

Natural products present in the plant and animal kingdom offer a huge diversity of chemical structures which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate, and then determine the structures and biological activity of natural products rapidly, thus opening up exciting new opportunities in the field of new drug development to the pharmaceutical industry. The series also covers the synthesis or testing and recording of the medicinal properties of natural products.

目次

Phytoestrogens - "Estrogene Like" Phytochemicals The Discovery and Synthesis of Brevisamide Recent Asymmetric Syntheses of Tetrahydroisoquinolines Using "Named" And Some Other Newer Methods 1-Methoxy-Canthin-6-One and Related ?-Carbolines: From Natural Compound to Synthesis and Biological Activities Fern Acylphloroglucinols: Structure, Location, and Biological Effects Mitogen-Activated Protein Kinase and Natural Phenolic Compounds in Cardiovascular Remodeling Chemistry and Biological Activity of Diterpenoid Alkaloids Novel Plant Derived Biomedical Agents and Their Biosynthetic Origin Histone Deacetylases as Cancer Chemoprevention Targets For Natural Products Natural Products: Strategic Tools for Modulation of Biofilm Formation Medicinal Herbs and Plant Extracts for Influenza: Bioactivity, Mechanism of Anti-Influenza Effects and Modulation of Immune Responses Natural Herbicides as a Safer and More Environmentally Friendly Approach to Weed Control. A Review of the Literature Since 2000 Recent Approaches towards Selected Lamiaceae Plants for Their Prospective Use in Neuroprotection Phytochemicals: In Pursuit of Anti-Tubercular Drugs Subject Index

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[v. 49] ISBN 9780444636010

内容説明

Studies in Natural Products Chemistry: Bioactive Natural Products (Part XII) is the latest in a series that covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis, and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to quickly isolate and determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry.

目次

1. Echinoderms: A Review of Bioactive Compounds with Potential Health Effects 2. Sea Cucumber Triterpene Glycosides as Anticancer Agents 3. Cytotoxic Alkaloid Constituents of the Amaryllidaceae 4. Bioactivity and Synthesis of Diarylheptanoids from Alpinia Officinarum 5. Bioactive Secondary Metabolites from Endophytic Fungi: A Review of Biotechnological Production of and their Potential Applications 6. Natural Product Inhibitors of Ubiquitin Conjugation and Deconjugation 7. Sesquiterpene Lactones: Structural Diversity and Perspectives as Anti-Inflammatory Molecules 8. Application of Monoclonal Antibodies against Ginsenosides in the Field Of Ginseng Studies 9. The Chemistry of Mushrooms: A Survey of Novel Extraction Techniques targeted to Chromatographic and Spectroscopic Screening 10. Carbohydrate- Based Therapeutics: A Frontier in Drug Discovery and Development 11. Biologically Active Compounds from the Genus Centaurium s.l. (Gentianaceae): Current Knowledge and Future Prospects in Medicine

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[v. 48] ISBN 9780444636027

内容説明

Studies in Natural Products Chemistry, Volume 48, provides the latest on the use of natural products from the plant and animal kingdom and the ways in which they can offer a huge diversity of chemical structures, which are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then rapidly determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development. The series covers all aspects of the science, along with the synthesis, testing, and recording of the medicinal properties of natural products. With articles written by leading authorities in their respective fields of research, the book presents current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products. It is a valuable resource for all those working in natural product and medicinal chemistry.

目次

Recent Accomplishments in the Total Synthesis of Natural Products through C - H Functionalization Strategies V. DOMINGO, J. F. QUILEZ DEL MORAL and A. F. BARRERO Synthetic Studies toward Nonribosomal Peptides INDRANIL DUTTAGUPTA, KESHAB CH. GHOSH and SURAJIT SINHA The Anti-Inflammatory Potential of Flavonoids: Mechanistic Aspects MARCELO D. CATARINO, OUALID TALHI, AMAL RABAHI, ARTUR M.S. SILVA and SUSANA M. CARDOSO Comparative Studies in Relation to the Structure and Biochemical Properties of the Active Compounds in the Volatile and Nonvolatile Fractions of Turmeric (C. Longa) and Ginger (Z. Officinale) JAMES N. JACOB 7-6-5 Tricarbocyclic Diterpenes: Valparanes, Mulinanes, Cyathanes, Homoverrucosanes and Related Ones ISIDRO S. MARCOS, ROSALINA F. MORO, ANA GIL-MESON and DAVID DIEZ Fructooligosaccharides: A Review on their Mechanisms of Action and Effects GUOCHUANG CHEN, CHAOPIN LI and KAOSHAN CHEN Psychotria Genus: Chemical Constituents, Biological Activities and Synthetic Studies ALMIR RIBEIRO DE CARVALHO JUNIOR, MARIO GERALDO DE CARVALHO, RAIMUNDO BRAZ FILHO and IVO JOSE CURCINO VIEIRA Recent Developments in Natural Product Based Drug Discovery in Tropical Diseases UMA R. LAL and AMRIT SINGH Selected Bioactive Natural Products for Diabetes Mellitus NISHIKANT A. RAUT, PRADIP W. DHORE, SUPRIT D. SAOJI and DADASAHEB M. KOKARE 342 Studies on Prodelphinidins: Isolation, Synthesis, and their Biological Activities HIDEFUMI MAKABE Endolichenic Fungi: A Potential Treasure Trove for Discovery of Special Structures and Bioactive Compounds HAO GAO, JIAN ZOU, JUN LI and HUAN ZHAO Superfood and Medicines Based on Bioactive Substances Derived from Cyanobacteria MAGDALENA B. ZARZYCKA, BOZENA FENERT and PAWEL K. ZARZYCKI Natural Products of Actinobacteria Derived from Marine Organisms VALLIAPPAN KARUPPIAH, WEI SUN and ZHIYONG LI

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[v. 47] ISBN 9780444636034

内容説明

Studies in Natural Products Chemistry contains the latest articles written by leading authorities in their respective fields of research, presenting current frontiers and future guidelines for research based on important discoveries made in the field of bioactive natural products. It is an invaluable resource for anyone working in natural product and medicinal chemistry.

目次

1. Topoisomerase I Inhibitors Derived from Natural Products: Structure-Activity Relationships and Antitumor Potency, Chunquan Sheng et al. 2.Isolation and Identification of Enediynes and Cycloaromatized Derivatives, M. S. Vela Gurovic 3. Natural Substances from Higher Plants as Potential Anti-MRSA Agents, Gyoergyi Horvath et al. 4. Multi-targeted Bioactive Materials of Plants in the Curcuma Genus and Related Compounds: Recent Advances, Miguel E. Alonso-Amelot 5. Novel Diarylheptanoids and Metabolism and Bioavailablity of Curcumin, Jeevan K. Prasain And Stephen Barnes 6. Antiulcerogenic Compounds Isolated from Medicinal Plants, Fernando Pereira Beserra, et al. 7. The Total Synthesis of (-)-Tetrodotoxin: A Historical Account, Carlos A. Valdez 8. Chiral Acyclic PNA Modifications: Synthesis and Properties, A. M. Varizhuk et al. 9. Marine-Derived Fungi: Source of Biologically Potent and Novel Compounds, Mahesh S. Majik et al. 10. Recent Advances in the Chemistry and Chemical Biology of Quorum-Sensing Pheromones and Microbial Hormones, Arata Yajima 11. Exogenous and Endogenous Mediators of Oxygen Metabolism: Alternatives for Chemical and Biological Activity, Galina F. Fedorova et al. 12. Recent Advances for Synthesis of Scyphostatin and Utilization of Oxabicyclo[2.2.1]Heptene toward Ethyl Shikimate, Kazuaki Kuwata et al. 13. Isolation, Total Synthesis and Biological Activities of 1-Aminocyclopropane-1-carboxylic Acid (ACC) Containing Natural Compounds, Michael G. Coleman and Andre O. Hudson

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[v. 50] ISBN 9780444637499

内容説明

Studies in Natural Products Chemistry: Bioactive Natural Products (Part XIII) is the latest in a series that covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis, and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to quickly isolate and determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry.

目次

Chapter 1. Synthesis and Structure-Activity Relations in Allylsulfide and Isothiocyanate Compounds From Garlic and Broccoli Against In Vitro Cancer Cell Growth Chapter 2. Natural Products as Lead Protein Kinase C Modulators for Cancer Therapy Chapter 3. Plant-Derived Prooxidants as Potential Anticancer Therapeutics Chapter 4. Anticancer and Antineurodegenerative Effects of Ginsenosides Chapter 5. Role of Phytochemicals in MAPK Signaling Pathway-Mediated Apoptosis: A Possible Strategy in Cancer Chemoprevention Chapter 6. Natural Products as Cathepsin Inhibitors Chapter 7. Endemic Plants of Italy and Their Peculiar Molecular Pattern Chapter 8. From Natural Products to Drugs: Glyco- and Lipoglycopeptides, a New Generation of Potent Cell Wall Biosynthesis Inhibitors Chapter 9. CH Bond Activation as a Powerful Tool in the Construction of Biologically Active Nitrogen-Containing Heterocycles Chapter 10. Isolation, Bioactivity, and Synthesis of Nagelamides Chapter 11. Nutraceuticals Neuroprotect Naturally: Alzheimer's disease, Parkinson's disease, Stroke and Major Depressive Disorder Chapter 12. Nanotechnology-Based Approach for Enhanced Bioavailability and Stability of Tea Polyphenols-A Review

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[v. 54] ISBN 9780444639295

内容説明

Studies in Natural Products Chemistry, Volume 54, covers the synthesis, testing and recording of the medicinal properties of natural products, providing cutting edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry.

目次

1. A Conserved Family of DNA-Binding Peptides as New Potential Natural Antitumor Agents 2. Recent Advances in the Chemistry of Natural and Semisynthetic Topoisomerase I/II Inhibitors 3. Hopanoids in Cyanobacteria Biomass and Related Samples 4. Antibacterial Potential of Diterpenoids 5. Chemistry and Bioactivity of ent-Kaurene Diterpenoids 6. Bioactive Compounds from Microalgae: Current Development and Prospects 7. Tabernaemontana Species: Promising Sources of New Useful Drugs 8. Plant-derived Anti-Diabetic Compounds Obtained from African Medicinal Plants: A Short Review 9. Homoisoflavonoids: Occurrence, Biosynthesis and Biological Activity 10. Anticancer Curcumin: Natural Analogues and Structure-Activity Relationship

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[v. 53] ISBN 9780444639301

内容説明

Studies in Natural Products Chemistry, Volume 53, covers the synthesis, testing, and recording of the medicinal properties of natural products, providing cutting-edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis, and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then determine the structures and biological activity of natural products rapidly, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry that are discussed and highlighted in this series.

目次

1. Pharmacology and Structure-Activity Relationship of Natural Products With Psychoactive Effects From Salvia divinorum, Mitragyna speciosa, and Ayahuasca 2. Recent Developments on the Synthesis and Applications of Betulin and Betulinic Acid Derivatives as Therapeutic Agents 3. Synthetic Approaches to the Naturally Occurring Anticancer Amaryllidaceae Alkaloids trans-dihydrolycoricidine and trans-dihydronarciclasine 4. Total Synthesis of Schisandra Nortriterpenoids: History, Progress, and Perspective 5. Chemical Synthesis of Meridianins and Related Derivatives 6. Biologically Active Isothiocyanates: Protecting Plants and Healing Humans 7. Curcumin, a Multitarget Phytochemical: Challenges and Perspectives 8. Bioactive Coumarins and Xanthones From Calophyllum Genus and Analysis of Their Druglikeness and Toxicological Properties 9. Structure and Biological Functions of d-Glucans and Their Applications 10. Chemistry, Bioactivity, and the Structure-Activity Relationship of Cephalotaxine-Type Alkaloids From Cephalotaxus sp. 11. Analysis of the Protein Binding Sites for Thiamin and Its Derivatives to Elucidate the Molecular Mechanisms of the Noncoenzyme Action of Thiamin (Vitamin B1)

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[v. 52] ISBN 9780444639318

内容説明

Studies in Natural Products Chemistry covers the synthesis, testing, and recording of the medicinal properties of natural products, providing cutting-edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis, and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to isolate and then rapidly determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development in the pharmaceutical industry.

目次

1. Natural Environments for Nanoparticles Synthesis of Metal, Metal Oxides, Core-Shell and Bimetallic Systems 2. 2-Aminoimidazoles: Synthesis by Ring Transformation Reactions 3. Strategies for Total Synthesis of Furanocembranolides and Related Natural Products From Marine Organisms 4. Phyllobilins: A New Group of Bioactive Compounds 5. Artemisinin the Nobel Molecule: From Plant to Patient 6. Bioactive Polyphenols for Diabetes and Inflammation in Psoriasis Disease 7. Nonhalogenated Heterotricyclic Sesquiterpenes From Marine Origin I: Fused Systems 8. Phytochemicals With Antileishmanial Activity: Prospective Drug Targets 9. Parthenolide and Parthenolide-Like Sesquiterpene Lactones as Multiple Targets Drugs: Current Knowledge and New Developments 10. Alkaloids From Apocynaceae: Origin, Pharmacotherapeutic Properties, and Structure-Activity Studies

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[v. 58] ISBN 9780444640567

内容説明

Studies in Natural Products Chemistry, Volume 58, covers the synthesis, testing and recording of the medicinal properties of natural products, providing cutting edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to rapidly isolate and determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development in the pharmaceutical industry.

目次

• 1. Plant Lectins: Bioactivities and Bioapplications 2. The Role of NADP(H) Oxidase Inhibition and its Implications in Cardiovascular Disease Management using Natural Plants Products 3. The Current and Potential Therapeutic uses of Parthenolide 4. Caged Garcinia Xanthones: Synthetic Studies and Pharmacophore Evaluation 5. Phytoestrogens as Potential Therapeutic Agents for The Treatment of Anxiety and Affective Disorders 6. Applications of Flavonoids, with an emphasis on Hesperidin, as Anticancer Pro-Drugs: Phytotherapy as an alternative to Chemotherapy 7. Augmented Cell Signaling by Natural Polyphenols and Flavonoids: Insights into Cancer Cell Remodeling and Prevention 8. Beneficial Effects of Anthocyanin from Natural Products On Lifestyle-Related Diseases Through Inhibition of Protease Activities 9. Quercetin: Pro-Oxidant Effect and Apoptosis in Cancer 10. Bioactive Components of Saffron and their Pharmacological Properties 11. Anthraquinones: An Overview 12. The Genus Hymenaea (Fabaceae): A Chemical and Pharmacological Review 13. Phenolic Acids from Plants
• Extraction and Application to Human Health 14. Cannabidiol (CBD) in Refractory Epilepsy

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[v. 57] ISBN 9780444640574

内容説明

Studies in Natural Products Chemistry, Volume 57, covers rapid developments in spectroscopic techniques and advances in high-throughput screening techniques that have made it possible to rapidly isolate and determine the structures and biological activity of natural products in new drug development. The series also covers the synthesis of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. Specific sections in this release cover broad-spectrum health protection of extra virgin olive oil compounds, synthesis of cardiac steroids and their role on heart failure and cancer, and more.

目次

1. Naturally occurring cyclobutanes: Their biological significance and synthesis 2. Broad-spectrum health protection of extra virgin olive oil compounds 3. Synthesis of cardiac steroids and their role on heart failure and cancer 4. Phenolic derivatives from medicinal herbs and plant extracts: Anticancer effects and synthetic approaches to modulate biological activity 5. Oligosaccharides from colostrum and dairy by-products: Determination, enrichment and healthy effects 6. Curcumin from turmeric as an adjunct drug? 7. Isolation and characterization of phenolic compounds from selected foods of plant origin using modern spectroscopic approaches 8. Fungal natural products focused on combating helminthiases 9. Phytochemistry, ethnomedicine and pharmacology of Acacia 10. Natural products with quorum quenching-independent antivirulence properties 11. Natural bioactive molecules with antidiabetic attributes: Insights into structure-activity relationships 12. Olea Europaea as potential source of bioactive compounds for diseases prevention 13. y-Aminobutyric acid (Gaba): Biosynthesis, role, commercial production and applications

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[v. 56] ISBN 9780444640581

内容説明

Studies in Natural Products Chemistry, Volume 56 covers rapid developments in spectroscopic techniques, also presenting advances in high-throughput screening techniques, including the new potential to isolate and determine the structures and biological activity of natural products and their applications in the field of new drug development. This ongoing series covers the synthesis, testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products.

目次

1. Novel approaches in the synthesis of natural and synthetic fused aza-polycycles towards the development of new bioactive compounds 2. Combretastatins: Plant anti-cancer phenolics 3. The role of natural products in Alzheimer's and Parkinson's disease 4. Nature's medicines to treat epileptic seizures 5. Effects of bioactive components of green tea on Alzheimer's disease 6. Anti-HIV agents from nature: Natural compounds from Hypericum hircinum and carbocyclic nucleosides from iridoids 7. Bioactive natural products in plant disease control 8. Flavonoid alkaloids: Isolation, bioactivity and synthesis 9. Amides from plants: Structures and biological importance 10. Milk as a natural product: Foreign natural and anthropogenic organic compounds in it 11. Microencapsulation of phytosterols by spray drying

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[v. 55] ISBN 9780444640680

内容説明

Studies in Natural Products Chemistry, Volume 55 covers rapid developments in spectroscopic techniques, also presenting advances in high-throughput screening techniques, including the new potential to isolate and determine the structures and biological activity of natural products and their applications in the field of new drug development. This ongoing series covers the synthesis, testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products.

目次

1. Conventional and bio-inspired syntheses of monoterpene indole alkaloids 2. Stereoselective synthesis of natural products promoted by titanocene (III) 3. Macrocyclic bisbibenzyls: Properties and synthesis 4. Selected phyto and marine bioactive compounds: Alternatives for the treatment of type 2 diabetes 5. Cyclopropyl lactone-containing marine oxylipins 6. Natural polyphenols and terpenoids for depression treatment: Current status 7. Isolation and physical characterization of bioactive lipopolysaccharides (lipid A) from nontoxic E. coli of human origin 8. Hydroxycinnamic acids: Natural sources, biosynthesis, possible biological activities and roles in Islamic medicine 9. Natural acylated anthocyanins and other related flavonoids: Structure elucidation of ipomoea cairica compounds and QSAR studies including multidrug resistance 10. Endothelial protective effects of dietary phytochemicals, Focus on polyphenols and carotenoids 11. Ivy and licorice triterpene glycosides - promising molecular containers for some drugs and biomolecules 12. Amicoumacins and related compounds: Chemistry and biology

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[v. 59] ISBN 9780444641793

内容説明

Studies in Natural Products Chemistry, Volume 59, the latest in the series, covers the synthesis, or testing and recording, of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. Natural products in the plant and animal kingdom offer a huge diversity of chemical structures that are the result of biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, this book is a welcomed resource.

目次

1. Metabolic Screening of Wine (Grapevine) Resveratrol 2. Sweet Cherry Phenolic Compounds: Identification, Characterization and Health Benefits 3. Phenolic Compounds: A Good Choice Against Chronic Degenerative Diseases 4. Recent Developments in the Quest for Novel Microbial Natural Products 5. Mycosporine-Like Amino Acids as Multifunctional Secondary Metabolites in Cyanobacteria: From Biochemical to Application Aspects 6. Basic and Clinical Studies with Marine LipoFishins and Vegetal Favalins in Neurodegeneration and Age-Related Disorders 7. Terpenoids as Emerging Therapeutic Agents: Cellular Targets and Mechanisms of Action against Protozoan Parasites 8. Bioactive Sesquiterpene Coumarins From Plants 9. Assessing Herb-Drug Interactions of Herbal Products With Therapeutic Agents for Metabolic Diseases: Analytical and Regulatory Perspectives 10. Natural Products for the Management of Diabetes 11. Limonoids: Structure-Activity Relationship Studies and Anticancer properties 12. Anticancer Potential of Flavonoids: Chemistry, Biological Activities and Future Perspectives 13. Chemistry and Biology of Salicyl-Capped Siderophores 14. Southern Brazilian Hypericum Species, Promising Sources of Bioactive Metabolites 15. Citrus Polymethoxyflavones: Biofunctional Molecules of Therapeutic Interest

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[v. 60] ISBN 9780444641816

内容説明

Studies in Natural Products Chemistry, Volume 60 covers the synthesis, testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to rapidly isolate and determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development in the pharmaceutical industry.

目次

1. Metabolic Syndrome: Preventive Effects of Dietary Flavonoids 2. An Overview of Synthetic and Semisynthetic Flavonoid Derivatives and Analogues: Perspectives in Drug Discovery 3. Therapeutic Potentials of the Most Studied Flavonoids: Highlighting Antibacterial and Antidiabetic Functionalities 4. Synthesis of N-Linked Carbaoligosaccharides: Total Synthesis of Antibiotic Validamycins and Related Compounds 5. Siderophores: Amazing Metabolites of Microorganisms 6. Sources, Chemistry and Biological Potential of Ellagitannins and Ellagic Acid Derivatives 7. Antigenotoxic Potential of Some Dietary Non-phenolic Phytochemicals 8. In Vitro Biosynthesis of Polyphenols in the Presence of Elicitors and Upregulation of Genes of the Phenylpropanoid Pathway in Plantago ovata 9. Role Phytochemicals Play in the Activation of Antioxidant Response Element (ARE) and Phase II Enzymes and Their Relation to Cancer Progression and Prevention 10. Chemical Diversification of Natural Product Extracts 11. Endophytic Actinomycetes in the Biosynthesis of Bioactive Metabolites: Chemical Diversity and the Role of Medicinal Plants 12. Lichens as a Promising Source of Unique and Functional Small Molecules for Human Health and Well-Being 13. Bee Venom Composition: From Chemistry to Biological Activity 14. Natural Products Applied to Antimicrobial Coatings

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[v. 61] ISBN 9780444641830

内容説明

Studies in Natural Products Chemistry, Volume 61 discusses natural products in the plant and animal kingdom that offer a huge diversity of chemical structures resulting from biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to rapidly isolate and determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. This series covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products.

目次

1. A review of recent patents regarding antithrombotic drugs derived from natural products 2. Bioactive natural products from the genus kalanchoe as cancer chemopreventive agents: A review 3. Patents on natural products for diagnosing/preventing/treating alzheimer's disease 4. Cannabinoids: Extraction methods, analysis and physicochemical characterization 5. High-resolution mass spectrometry and biological properties of grapevine and wine stilbenoids 6. Raman spectroscopy- a key analytical tool for new drugs research and development 7. Chemical and biological perspectives of monoterpene indole alkaloids from rauwolfia species 8. Alkaloids as potential multi-target drugs to treat alzheimer's disease 9. Whole-cell bioconversion of citrus flavonoids to enhance their biological properties 10. Microbiological in vivo production of clna as a tool in the regulation of host microbiota in obesity control 11. Non-streptomyces actinomycetes and natural products: recent updates 12. An overview of the multifaceted lessons learned from marine-derived bioactive lamellarin natural products 13. Brominated molecules from marine algae and their pharmacological importance

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[v. 62] ISBN 9780444641854

内容説明

Studies in Natural Products Chemistry, Volume 62 discusses natural products in the plant and animal kingdom that offer a huge diversity of chemical structures resulting from biosynthetic processes that have been modulated over the millennia through genetic effects. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to rapidly isolate and determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development to the pharmaceutical industry. This series covers the synthesis or testing and recording of the medicinal properties of natural products, providing cutting-edge accounts of the fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products.

目次

1. Fungal metabolites as promising new drug leads for the treatment of alzheimer's disease 2. Mushrooms, seaweeds and their derivatives as functional feed additives for aquaculture: An updated view 3. Nanotechnology-based drug delivery of natural compounds and phytochemicals for the treatment of cancer and other diseases 4. Phytochemistry, chemotaxonomy, ethnopharmacology and nutraceutics of lamiaceae 5. Moringa oleifera Lam: A rich source of phytoactives for the health of human beings 6. Protease inhibitors and their applications: An overview 7. Plant terpenoids as lead compounds against malaria and leishmaniasis 8. Dalea genus, chemistry and bioactivity studies 9. Natural bioactive cyclic peptides and peptidomimetics 10. Pyrrole-derived alkaloids of marine sponges and their biological properties 11. Isolation and elucidation of anti-irritant and antimicrobial bioactive derived from plant sources and from human sebum 12. Bioactive quinolactacins and structurally related pyrroloquinolones

巻冊次

pt. A ISBN 9780444899378

内容説明

Natural products chemistry has evolved with growing emphasis on isolating bioactive natural compounds. The synthetic programmes are also directed towards bioactive natural products, many of which could hitherto only be obtained in small quantities from much larger quantities. However, they can be synthesized in much larger quantitities. Moreover, new analogues may be prepared which will have a higher activity and lower toxicity than the parent compounds. The present volume specifically covers the field of such bioactive natural products. It presents research being carried out on a wide variety of compounds, including oligonucleotides, bioactive terpenes, anti-tumour antibiotics, cytochalasans, indole alkaloids, flavours and biologically active carba-sugars. The in-depth presentations on some of the current frontiers of natural product chemistry should prove to be of wide interest to all organic chemists.

目次

• Synthesis of di- and triquinane sesqui-, di- and sesterterpenes - Columbus style, L.A. Paquette
• asymmetric synthesis of bioactive natural products and related compounds from chiral propane-1, 3-diols and analogues, M. Ihara and K. Fukumoto
• total synthesis of cytochalasans, E.J. Thomas
• synthetic modifications of the erythromycin A macrolactone - effects on biological activity, P.A. Lartey and T.J. Perun
• synthesis of biologically active compounds composed of carba-sugars, S. Ogawa
• automated synthesis, structure and biological activity of backbone-modified oligonucleotides - the antisense approach, A. Frauendorf and J.W. Engels
• new avenues in natural products - strategies in the biogeneration of flavours, C. Fuganti et al
• anticancer acridone alkaloids, Tsann-Lone Su and K.A. Watanabe
• the synthesis of macroline related indole alkaloids, Yingzhi Bi et al
• total synthesis of mitomycins, T. Fukuyama and L. Yang
• organosilicon compounds as nucleophiles in the synthesis of bioactive natural products via N-acyliminium intermediates, H. De Koning et al
• non-trichothecene secondary metabolites of fusarium - recent work, M.E. Savard and J.W. Apsimon
• naturally occurring mevinic acids - synthetic studies, T. Rosen
• pharmacognosy - new roots for an old science, G.A. Cordell.

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詳細情報

• NII書誌ID(NCID): BA19938783
• ISBN:
  • 0444899375
  • 0444504699
  • 0444505881
  • 0444506063
  • 0444506438
  • 0080440010
  • 0444510044
  • 0444512306
  • 0444514155
  • 0444515100
  • 0444518541
  • 0444521712
  • 0444527176
  • 9780444531803
  • 9780444531810
  • 9780444538369
  • 9780444595140
  • 9780444595300
  • 9780444636034
  • 9780444636027
  • 9780444636010
  • 9780444637499
  • 9780444639318
  • 9780444639301
  • 9780444639295
  • 9780444640680
  • 9780444640581
  • 9780444640574
  • 9780444640567
  • 9780444641793
  • 9780444641816
  • 9780444641830
  • 9780444641854
  • 9780128179017
  • 9780128179031
• 出版国コード: ne
• タイトル言語コード: eng
• 本文言語コード: eng
• 出版地: Amsterdam ; Tokyo
• ページ数/冊数: v.
• 大きさ: 25 cm
• 分類:
  • LCC : QD415.A2
  • DC19 : 547.7
• 件名:
  • LCSH : Natural products
• 親書誌ID:
  • BA04899553