The basis of toxicity testing

Bibliographic Information

The basis of toxicity testing

Donald J. Ecobichon

(Pharmacology & toxicology)

CRC Press, c1992

Available at  / 5 libraries

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Note

Includes bibliographical references and index

Description and Table of Contents

Description

This book discusses fundamental principles and concepts behind toxicological tests, their design and implementation, interpretation of results, and significance of individual studies in the overall assessment of toxicants. It covers the complete spectrum of toxicological investigations required for the registration of a chemical (including in vivo and in vitro studies); describes the design of toxicological studies in simple terms, reinforced with diagrams of their design, possible results, and interpretation; examines the various factors that can affect the outcome of a toxicological study; and discusses the limitations of various toxicological tests and their significance in the overall process of hazard and risk evaluation. The book is intended for researchers in toxicology, pharmacology, industrial hygiene, occupational health, nutrition, animal studies, food technology and pesticides.

Table of Contents

  • Preliminary considerations
  • acute toxicity studies
  • subchronic and chronic studies
  • reproductive toxicology
  • mutagenesis-carcinogenesis
  • risk assessment.

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Details

  • NCID
    BA1994595X
  • ISBN
    • 0849378141
  • LCCN
    91031579
  • Country Code
    us
  • Title Language Code
    eng
  • Text Language Code
    eng
  • Place of Publication
    Boca Raton
  • Pages/Volumes
    x, 160 p.
  • Size
    26 cm
  • Classification
  • Subject Headings
  • Parent Bibliography ID
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