Alzheimer's disease : advances in clinical and basic research

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書誌事項

Alzheimer's disease : advances in clinical and basic research

edited by Benedetto Corain ... [et al.]

J. Wiley, c1993

大学図書館所蔵 件 / 全9件

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Alzheimer disease is one of the most devastating brain diseases of middle-aged and elderly humans. This disease is not only a social and an economic tragedy of major proportions in modern society, but it also represents a great scientific challenge. To date, the etiology and the pathogenesis of Alzheimer's disease remain elusive. Considerable progress has been made toward understanding the basic molecular mechanisms of the disease and toward developing diagnostic and therapeutic strategies. This volume provides comprehensive coverage of these and other recent advances in the areas of diagnosis and clinical evaluation, neuroimaging, brain energy metabolism, biomarkers, risk factors and epidemiology, structural and molecular neuropathology, mechanisms of neuronal degeneration, brain amyloidosis, metabolic factors, environmental factors, genetic mechanisms, cellular and animal models, and therapeutic strategies. Chapters are also devoted to the similarities and differences between transmissible dementias and Alzheimer disease.

目次

  • Partial table of contents:
  • DIAGNOSIS AND BIOMARKERS
  • A Rational Clinical Approach to Patients with Dementia (A. Wallin & K. Blennow)
  • Tau and Ubiquitin as Markers for Alzheimer's Disease (I. Grundke-Iqbal & K. Iqbal)
  • An Abnormality of Plasma A4 Amyloid Protein Precursor in Alzheimer's Disease (S. Whyte, et al.)
  • EPIDEMIOLOGY AND RISK FACTORS
  • Descriptive Epidemiology and Risk Factors for Alzheimer's Disease (L. Amaducci, et al.)
  • STRUCTURAL PATHOLOGY, PATTERNS OF CELL LOSS AND THE BLOOD-BRAIN BARRIER
  • Involvement of the Visual Thalamus in Alzheimer's Disease (G. Leuba & K. Saini)
  • MECHANISMS OF CELL DEATH: GENETIC FACTORS
  • Inheritance of Multiple Loci in Familial Alzheimer's Disease (J. Haines, et al.)
  • TRANSMISSIBLE DEMENTIAS
  • Neurodegeneration and Prion Diseases (S. Prusiner)
  • THERAPEUTICS
  • Pharmacotherapy of Alzheimer's Disease: New Drugs and Novel Strategies (E. Giacobini)
  • Index.

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