High performance liquid chromatography in neuroscience research

著者

書誌事項

High performance liquid chromatography in neuroscience research

edited by R. Bruce Holman, Alan J. Cross, and Michael H. Joseph

（IBRO handbook series : methods in the neurosciences, v. 15）

J. Wiley, 1993

  • : pbk

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

This volume covers the principles of High Performance Liquid Chromatography (HPLC) and the principles of methods development for neuroscience applications. The primary emphasis is on detailed and functional descriptions of methods for a wide range of specific groups of neurochemicals. The final chapter reviews the application of HPLC to the analysis of central nervous system (CNS) active drugs. As well as providing a brief overview of the choice of methodologies, the contributors focus on specific method(s) to provide the maximum amount of practical information based on personal experience, illustrated by material from the analysis of real biological samples.

目次

  • Theoretical and Practical Basis of HPLC
  • Preparation, Separation and Detection
  • Monoamines and Metabolites in Brain
  • Monoamines and Metabolites in Body Fluids
  • Acetylocholine
  • GABA and Glutamate
  • Other Amino Acids
  • Sulphur-Containing and Neurotoxic Amino Acids
  • Nucleosides, Bases and Related Compounds
  • Inositol Phosphates
  • Trace Amines and Histamine
  • Amine Related Co-Factors and Other Compounds
  • Peptides: Detection, Sequencing, Identification
  • Metabolism of Peptides
  • General Methodology for Identification of Drugs in Brain and Body Fluids.

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