Bibliographic Information

Molecular biology and its application to medical mycology

edited by Bruno Maresca, George S. Kobayashi, Hideyo Yamaguchi

(NATO ASI series, Series H . Cell biology ; vol. 69)

Springer-Verlag, c1993

  • : Berlin
  • : New York

Available at  / 9 libraries

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Note

"Proceedings of the NATO Advanced Research Workshop on Molecular Biology and Its Application to Medical Mycology, held at Taormina, Italy, January 6-8, 1992"--T.p. verso

"Published in cooperation with NATO Scientific Affairs Division."

Includes bibliographical references and index

Description and Table of Contents

Description

Presented here are recent achievements in the molecular biology of non-pathogenic yeast and filamentous fungi as well as human pathogens. The book is divided into four sections: molecular biology of yeast; molecular biology of filamentous fungi; new tools and prospectives for medical mycology; and fungal morphogenesis. It focuses on aspects of medical mycology; namely the isolation of specific genes and strategies for developing new targets for antifungal therapy.

Table of Contents

Molecular Biology of Yeast.- Cell Cycle Regulation in Fission Yeast.- Yeast Genes Overcoming Growth Arrest Induced by 1,10-Phenanthroline.- Reverse Genetics in a Non-Conventional Yeast, Candida maltosa.- The Complement C3D-Binding Receptor (CR2) of Candida albicans: Cloning and Sequence Analysis of a Gene Fragment Homologous with a Human CR2 cDNA Clone.- Biology, Physiology, Biochemistry and Molecular Genetics of Trichosporon Yeasts.- Physiological Functions of Vacuoles in Yeast: Mechanism of Sequestration of Metabolites and Proteins into Vacuoles.- Characterization of a Candida albicans-Specific DNA Fragment.- Recent Advances in the Molecular Biology of Cryptococcus neoformans.- Molecular Biology of Kluyveromyces lactis.- Gene Regulatory Circuits in S. cerevisiae as a Tool for the Identification of Heterologous Eukaryotic Regulatory Elements.- Molecular Biology of Filamentous Fungi.- Molecular Breeding in Filamentous Fungi with Emphasis on Aspergilli.- TubB ?-Tubulin is Essential for Sexual Development in Aspergillus nidulans.- The Heat Shock Response of Neurospora crassa.- Blue Light Regulated Expression of Geranylgeranyl Pyrophosphate Synthetase (Albino-3) Gene in Neurospora crassa.- Expression of Genes for the Biosynthesis of Penicillin.- New Tools and Prospectives for Medical Mycology.- Imaging of the Yeast Killer Phenomenon.- cDNA Cloning of Candida albicans Aspartic Proteinase and Its Diagnostic Application.- Molecular Biotyping of Candida in Experimental and Clinical Studies.- Homoserine Dehydrogenase as a Selective Target Molecule for Antifungal Action.- Molecular Mechanisms of Antifungal Activity and Fungal Resistence: Focus on Inhibitors of Ergosterol Biosynthesis.- Molecular Studies on Azole Sensitivity in Fungi.- Antifungal Chemotherapy and Drug Strategies: Projected Clinical Needs.- Funding Medical Mycology: Strategies for Attracting the Private Sector.- Fungal Morphogenesis.- Chromosomal Organization of Histoplasma capsulation.- Chitin, Chitin Synthase and Chitin Synthase Conserved Region Homologues in Wangiella dermatitidis.- Heat Shock Response and Adaptation during Morphogenesis in Histoplasma capsulatum.

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