Pathophysiology of lysosomal transport
著者
書誌事項
Pathophysiology of lysosomal transport
CRC Press, c1992
大学図書館所蔵 全3件
  青森
  岩手
  宮城
  秋田
  山形
  福島
  茨城
  栃木
  群馬
  埼玉
  千葉
  東京
  神奈川
  新潟
  富山
  石川
  福井
  山梨
  長野
  岐阜
  静岡
  愛知
  三重
  滋賀
  京都
  大阪
  兵庫
  奈良
  和歌山
  鳥取
  島根
  岡山
  広島
  山口
  徳島
  香川
  愛媛
  高知
  福岡
  佐賀
  長崎
  熊本
  大分
  宮崎
  鹿児島
  沖縄
  韓国
  中国
  タイ
  イギリス
  ドイツ
  スイス
  フランス
  ベルギー
  オランダ
  スウェーデン
  ノルウェー
  アメリカ
注記
Includes bibliographical references and index
内容説明・目次
内容説明
The field of lysosomal transport has grown exponentially in the past decade. Research in this previously unknown function of lysosomes has resulted in understanding the metabolic defect in three inborn errors in metabolism: nephropathic cystinosis, cobalamin F-deficient methylmalonic aciduria, and Salla disease. Seventeen transport systems mediating the exodus from lysosomes of amino acids, sugars, nucleosides, phosphate, calcium, cobalamin, and sulfate have been described.
Pathophysiology of Lysosomal Transport presents the current status in this field as described by the authors who made the original discoveries. Each chapter examines the pathological consequences resulting from a defect in a particular system. The book also examines the transfer of macromolecules into the lysosomes, describes the analogy between mammalian lysosomes and vacuoles of plants and fungi, and reviews non-mediated transport. A comprehensive chapter on the methodology required to perform lysosomal studies will benefit researchers undertaking investigations in this area.
目次
INTRODUCTION (Jess Thoene). APPROACHES TO THE STUDY OF LYSOSOMAL TRANSPORT (Alice Greene and Jerry Schneider). LYSOSOMAL TRANSPORT OF AMINO ACIDS. Lysosomal Cystine Transport (William Gahl). Lysosomal Transport of Small and Large Neutral Amino Acids (Hans Andersson). Lysosomal Transport Systems for Cationic and Anionic Amino Acids: Systems c and d (Ronald Pisoni). LYSOSOMAL TRANSPORT OF INORGANIC IONS. The Transport of Phosphate and Calcium by Human Fibroblast Lysosomes (Ronald Pisoni and Jess Thoene). Lysosomal Sulfate Transport (Jaydutt Vadgama and Adam Jonas). LYSOSOMAL TRANSPORT OF OTHER METABOLITES. Lysosomal Nucleic Acid Catabolism and Carrier Mediated Transport of Nucleosides (Ronald Pisoni and Jess Thoene). Lysosomal Transport of Sugars: Normal and Pathological (Frank Tietze). Lysosomal Cobalamin Transport (Susan Sillaots and David Rosenblatt). TRANSPORT OF MACROMOLECULES TO LYSOSOMES (Hsiang-Kuang Lee and Louis Marzella). PASSIVE DIFFUSION ACROSS THE LYSOSOME MEMBRANE (John Lloyd). VACUOLES OF PLANTS AND FUNGI (John-Michael Idriss).
「Nielsen BookData」 より