Hormonal carcinogenesis : proceedings of the First International Symposium
著者
書誌事項
Hormonal carcinogenesis : proceedings of the First International Symposium
Springer-Verlag, c1992
大学図書館所蔵 件 / 全2件
-
該当する所蔵館はありません
- すべての絞り込み条件を解除する
注記
"First International Symposium on Hormonal Carcinogenesis was convened in Cancun, Mexico."--P. x
Includes bibliographical references and index
内容説明・目次
- 巻冊次
-
ISBN 9780387977973
内容説明
In the past decade there has been a growing public interest and resurgence in research in the field of hormonal carcinogenesis. This is due to the widespread use of therapeutic hormonal agents worldwide and to the increasing awareness of the causal association of hormones, both endogenous and exogenously administered, and a variety of human cancers. These associations include estrogens in uterine, cervical, vaginal, liver, testicular, prostatic, and possible breast cancers; progesterone and progestational hormones in breast cancer; androgens and anabolic steroids in hepatic and prostatic cancers. Additionally, gonadotrophins playa role in the etiology of ovarian and testicular cancers and thyroid-stimulating hormones in thyroid cancers. Therefore, hormonal carcinogenesis encompasses the study of both natural and synthetic hormonal agents, including growth factors and other peptide and protein factors, which contribute substantially to the etiology of both human and animal neoplasms, benign or malignant. Hormones may be involved in all aspects of neoplastic transformation, including initiation, promotion, and progression, and the inhibition of these processes. There are a number of important issues in women's health that need to be addressed. More than 40 million U. S. women are menopausal, and these women have a life expectancy of over 30 years after the menopause. When these figures are multiplied worldwide, the numbers become staggering. After the menopause, estrogen replacement therapy (ERT) is the choice of most women in industrialized countries.
- 巻冊次
-
ISBN 9783540977971
内容説明
An increasing awareness has emerged in recent years of an association between therapeutic hormonal agents and a variety of human cancers, including uterine, ovarian, cervical, vaginal, liver, testicular, prostatic, breast, hepatic and thyroid cancers. Concomitantly, there has been a resurgence in hormonal carcinogenesis research, a field that studies the involvement of both natural and synthetic hormonal agents in all aspects of neoplastic transformation in humans and animals. In this volume, contributors present state-of-the-art research regarding the current understanding of the normal physiologic, biochemical and molecular processes by which hormones affect cell proliferation and differentiation and neoplastic processes.
目次
- Sex hormones and carcinogenesis
- hormones, cell proliferation and carcinogenesis
- estrogen metabolism and carcinogenicity
- hormones and tumour promotion
- growth factors and oncogenes
- carcinogenesis risk assessment of sex hormones.
「Nielsen BookData」 より