Alzheimer's disease and related disorders : selected communications : proceedings of the IIIrd International Conference on Alzheimer's Disease and Related Disorders held in Padova, Italy on 12-17 July 1993
著者
書誌事項
Alzheimer's disease and related disorders : selected communications : proceedings of the IIIrd International Conference on Alzheimer's Disease and Related Disorders held in Padova, Italy on 12-17 July 1993
（Advances in the biosciences, v. 87）
Pergamon Press, c1993
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内容説明・目次
内容説明
The Third International Conference on Alzheimer's Disease and Related Disorders attracted over 1000 leading scientists involved in this dynamic field of research. This volume brings together a selection of stimulating presentations from the meeting, providing insights into research on Alzheimer's disease. The scope of the book extends to the following areas: diagnosis and clinical evaluation, biomarkers, structural and biochemical pathology, neuronal dysfunction, cytoskeletal protein alterations, amyloidosis, environmental toxins, blood brain barrier and immunological factors, animal and cellular models, epidemiology, pharmacological treatment and psycosocial management. The book is a major addition to the understanding of Alzheimer's disease and should appeal to neuroscientists everywhere.
目次
Diagnosis and Clinical Evaluation. Changes of hexokinase activity with age: relevance to Alzheimer's disease (P. Antuono et al.). Biomarkers. A rational approach to the study of biochemical diagnostic markers of Alzheimer's disease (K. Blennow, A. Wallin). Structural and Biochemical Pathology. A morphometric analysis of cerebral cortical neurons in progessive supranuclear palsy (J.G. Bautista et al.). Neuronal Dysfunction. Superoxide dismutase in ageing brain and related degenerative diseases (F. Bracco et al.). Cytoskeletal Protein Alterations. Tau protein phosphorylation by protein kinase C and proline-directed protein kinases: implications in Alzheimer's disease (I. Correas et al.). Amyloidosis. Bulbus ocull with amyloid deposits in old age and in patients with senile dementia of Alzheimer type (J. Bohl, E. Fontanji). Environmental Toxins. Interaction of aluminium with the mammalian mitochondrial outer membrane (C. Ballarin et al.). Blood Brain Barrier and Immunilogical Factors. Amyloid precursor protein (APP) is rapidly expressed in glia associated with reactive neurons. Early and rapid de novo-synthesis of APP in activated microglia (R.B. Banati et al.). Animal and Cellular Models. Behavioural and neurochemical effects of lesions in the nucleus basalis macnocellulan's of the rat (A. Adem et al.). Epidemiology. Association between low economic level and dememtia (M. Mele et al.). Pharmacological Treatment. The effects of cerebrolysin on survival and sprouting of neurons from cerebral hemispheres and from the brainstem of chick embryos in vitro (E. Albrecht et al.). Psycosocial Management. Carers of demented patients: life stvles and coping abilities (V. Puviani et al.). Round Table I - Ageing, Neurodegenerative Disorder and Mitochondria. The diagnosis and prevention of Alzheimer's disease: the role of 31P NMR (J.W. Pettegrew et al.). Round Table II - Cholinergic Approach to Age-Related Cognitive Dysfunctions. The diagnosis of early dementia investigation of a community sample with the Cambridge Mental Disorders of the elderly examination (Sir M. Roth). Round Table III Selective Inhibition of MAO in the Brain: A Drug Strategy to Improve the Quality of Life in the Elderly. Selective MAO-inhibition: a tool for a new pharmacological approach to degenerative disease (G.U. Corsini).
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