Gene transfer and therapy in the nervous system
著者
書誌事項
Gene transfer and therapy in the nervous system
（Research and perspectives in neurosciences）
Springer-Verlag, c1992
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注記
"This volume contains the proceedings of the meeting 'Gene Transfer and Therapy in the Nervous System' held in Paris on September 23, 1991"--Preface
Includes bibliographical references and index
内容説明・目次
内容説明
Gene transfer technology is a powerful tool for increasing our understanding of brain functions. It is also the basis of gene therapy, which is now technically possible for the correction of many human diseases, including several disorders of the nervous (and muscular) system such as Alzheimer's disease, Parkinson's disease and dystrophy. This volume, which contains the proceedings of a symposium of the Fondation Ipsen, provides a unique view of the state of the art on different transgenes, vectors, target cells and clinical applications.
目次
Somatic Cell Gene Therapy.- Delivery of Nerve Growth Factor Within the Rat Brain Using Genetically Modified Cells.- A Potential Approach to Gene Therapy of Cancer.- Phenotypic Plasticity and Neural Grafting.- The Sympathoadrenal Progenitor of the Neural Crest: Basic Biology and Therapeutic Potential.- Lineage, Migration, and Phenotype in Avian Optic Tectum: Analysis with Recombinant Retroviral Vectors.- Immortal Mammalian Neuronal Stem Cells Differentiate after Implantation into the Developing Brain.- Establishment of Clonal Cell Lines for the Study of Neural Function and Dysfunction.- Resistance of SOD-Transgenic Mice to Oxidative Stress.- Gene Transfer into the Nervous System using Recombinant Herpes Virus Vectors.- Development of Herpes Simplex Virus as a Gene Transfer Vector for the Central Nervous System.- Dystrophin mRNA Processing in the Canine Homologue of Duchenne Muscular Dystrophy: An Authentic Model for Gene Therapy.- Gene Transfer of a Murine Dystophin Minigene Construct.- Gene Therapy in Animal Models of Neurological Disorders.- Neurotrophins and their Receptors.- Regulation of the Human Neurofilament Light and Heavy Genes in Transgenic Mice.
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