The biology of the epidermis : molecular and functional aspects : proceedings of the Fifth Japan-United States Symposium on the Biology of the Epidermis, Niseko, Hokkaido, 21-25 July 1991

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書誌事項

The biology of the epidermis : molecular and functional aspects : proceedings of the Fifth Japan-United States Symposium on the Biology of the Epidermis, Niseko, Hokkaido, 21-25 July 1991

editors, Akira Ohkawara, Joseph McGuire

Elsevier, 1992

大学図書館所蔵 件 / 3

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注記

Includes bibliographical references and indexes

内容説明・目次

内容説明

The above mentioned congress, the fifth in a series of seminars held since 1976, was held under the sponsorship of The Japan Society for Promotion of Science and The National Science Foundation of the United States. The goal of these seminars has been to exchange the newest information and to discuss current topics in the field of epidermal proliferation and differentiation. The symposia have been published as four independent monographs which have drawn the interest of many biologists toward epidermal differentiation. The basic framework behind these seminars was established by the late Professor Makoto Seiji and by Professor Isadore A. Bernstein in 1976. They felt that a small group would be able to evaluate existing information, resolve differences of opinion and chart a direction which could result in more rapid progress toward the common goals sought by the participating laboratories in Japan and in the United States. The editors of this book hope that publication of these papers will be beneficial to investigators world-wide and will foster interaction among scientists in "The Biology of the Epidermis".

目次

  • Stratum corneum, biology and structural proteins Dynamics of epidermal barrier formation, function, and metabolism (P.M. Elias, et al.). The role of protein synthesis in permeability barrier homeostasis (J.S. Choi, et al.). Biological significance of photosensitized lipid peroxidation in drug-induced phototoxicity (I. Matsuo, et al.). Abnormality on the presence of keratohyalin granule protein in the patients with keratoderma (T. Tezuka, M. Takahashi). In vivo and in vitro measurements of water-holding capacity of the stratum corneum (H. Tagami, et al.). Regulation of movement, proliferation and differentiation. Mechanisms of human keratinocyte locomotion (J.D. Chen, et al.). The regulatory mechanism of keratinocyte migration during wound healing
  • Roles of plasminogen activator and growth factors (S. Morioka, et al.). Calcium regulation of epidermal cell physiology (J.A. Fairley, S.G. Arrindell). Histamine mobilizes calcium in cultured human keratincytes through H 1 -receptors (D.K. Maldonado, N.C. Krejci, J. McGuire). Involvement of protein kinase C in the control of cell-cell and cell-matrix junctions in relation to differentiation of keratinocytes (Y. Kitajima, et al.). Glucocorticoid induced regulation of beta2-adrenergic receptors in keratinocytes (H. Iizuka, H. Takahashi). Growth factors and oncogenes. Growth factors and intracellular control mechanisms of keratinocyte growth and differentiation (M.R. Pittelkow). The effect of vitamin D 3 on human keratinocytes and its me tabolism (K. Hashimoto, K. Matsumoto, K. Yoshikawa). Receptor tyrosine protein kinases in normal and malignant melanocytes (R. Halaban). Expression of proto-oncogenes in the regenerating of skin (H. Kobayashi, T. Nishikawa, A. Ohkawara). Cell cycle progression of cultured human epidermal keratinocytes after a single treatment with PUVA (S. Kawara, H. Sakai, T. Hirone). Development of transgenic mouse models of human skin diseases (D.R. Roop, et al.). Protein kinase C in skin: Its activation, down regulation, substrate proteins and family members. Immunological aspects. Major histocompatibility complex markers and molecular analysis of HLA-C genes in Japanese psoriatics (A. Asahina, et al.). Pivotal role of LFA-1/ICAM-1 adhesion in inflammatory skin disease: Therapeutic implications (B.J. Nickoloff). The immunological functions of keratinocytes (S. Shimada). Summary, Index of Authors.

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