The Chemistry of β-lactams

Bibliographic Information

The Chemistry of β-lactams

edited by Michael I. Page

Blackie Academic & Professional, 1992

1st ed

  • :USA

Other Title

The Chemistry of [beta]-lactams

Available at  / 4 libraries

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Note

Includes bibliographical references and index

Description and Table of Contents

Description

This volume provides a review of developments in the chemistry of beta-lactams, particularly in the synthesis, reactivity and mechanisms of reaction, including novel beta-lactam structures and non-beta-lactam analogues.

Table of Contents

  • The biosynthesis of beta-lactams, J.E. Baldwin and C. Schofield
  • structure-activity relationships - chemical, M.I. Page
  • - biological, H.C. Neu
  • the mechanisms of reactions of beta-lactams, M.I. Page
  • mode of action - interaction with the penicillin binding proteins, J.M. Frere et al
  • beta-lactamase - mechanism of action, S.G. Waley
  • beta-lactamase - inhibition, R.F. Pratt
  • novel beta-lactam structures - the carbacephems, R.D.G. Cooper
  • non-beta-lactam mimics of beta-lactam antibiotics, N. Junghein and R.J. Ternansky
  • classical beta-lactam structures, E.W. Colvin.

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