Bibliographic Information

Fundamentals of genetic epidemiology

Muin J. Khoury, Terri H. Beaty, Bernice H. Cohen

(Monographs in epidemiology and biostatistics, v. 19)

Oxford University Press, c1993

Available at  / 8 libraries

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Errata slip laid in

Includes bibliographical references (p. 340-377) and index

Description and Table of Contents

Description

Fundamentals of Genetic Epidemiology meets the need for a sophisticated approach to the investigation of the causes of complex chronic diseases. This integrated text describes the principles, methods, and approaches of epidemiology and genetics in the study of disease etiology. It provides an historical overview of genetics and epidemiology and their gradual rapprochement, describing the fundamental research strategies of genetic epidemiology including population and family studies. The authors also illustrate the increasing importance of genetic epidemiology in its application to preventive medicine, public health surveillance and the emerging ethical issues regarding the use of genetic information in society.

Table of Contents

  • 1. Scope and strategies of genetic epidemiology
  • 2. Fundamental genetic concepts and approaches
  • 3. Fundamental epidemiologic concpets and approaches
  • 4. Study of genetic traits
  • 5. Study of the genetic factors in disease
  • 6. Epidemiologic approaches to familial aggregation
  • 7. Genetic approaches to familial aggregation: Heritability
  • 8. Genetic approaches to familial aggregation: Segregation Analysis
  • 9. Genetic approaches to familial aggregation: Linkage Analysis
  • 10. Applications of genetic epidemiology in medicine and public health

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