書誌事項

Fundamentals of genetic epidemiology

Muin J. Khoury, Terri H. Beaty, Bernice H. Cohen

(Monographs in epidemiology and biostatistics, v. 19)

Oxford University Press, c1993

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注記

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Includes bibliographical references (p. 340-377) and index

内容説明・目次

内容説明

Fundamentals of Genetic Epidemiology meets the need for a sophisticated approach to the investigation of the causes of complex chronic diseases. This integrated text describes the principles, methods, and approaches of epidemiology and genetics in the study of disease etiology. It provides an historical overview of genetics and epidemiology and their gradual rapprochement, describing the fundamental research strategies of genetic epidemiology including population and family studies. The authors also illustrate the increasing importance of genetic epidemiology in its application to preventive medicine, public health surveillance and the emerging ethical issues regarding the use of genetic information in society.

目次

  • 1. Scope and strategies of genetic epidemiology
  • 2. Fundamental genetic concepts and approaches
  • 3. Fundamental epidemiologic concpets and approaches
  • 4. Study of genetic traits
  • 5. Study of the genetic factors in disease
  • 6. Epidemiologic approaches to familial aggregation
  • 7. Genetic approaches to familial aggregation: Heritability
  • 8. Genetic approaches to familial aggregation: Segregation Analysis
  • 9. Genetic approaches to familial aggregation: Linkage Analysis
  • 10. Applications of genetic epidemiology in medicine and public health

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