Descent of the testis
Author(s)
Bibliographic Information
Descent of the testis
Edward Arnold, 1992
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Note
Includes bibliographical references and index
Description and Table of Contents
Description
This book is an account of testicular descent and cryptorchidism. Both old and new theories of testicular descent are discussed and brought together in a unifying hypothesis which provides a fresh view of a complex problem. The clinical section of the book provides practical advice about diagnosis and an overview of surgical and medical treatment and then discusses the timing of surgery, the role of hormone treatment, and the potential for completely new forms of therapy. References are given at the end of each chapter.
Table of Contents
- Part 1 Evolution of descent of the testis and early history of research: evolution of testicular descent
- early work on testicular descent. Part 2 Transabdominal migration of the testis: the first hase of descent
- the gubernacular swelling reaction
- oestrogen-treated mouse
- persistent mullerian duct syndrome
- the role of mullerian inhibiting substance (MIS)
- conclusion. Part 3 Inguinoscrotal descent of the testis: migration of the gubernaculum
- intra-abdominal pressure
- the role of testosterone
- the genitofemoral nerve hypothesis
- sexual dimorphism of the genitofemoral nerve
- the effect of CGRP
- conclusion. Part 4 Classification and causes of undescended testes in humans: classification of undescended testes
- the incidence of undescended testis
- what causes cryptorchidism?
- cryptorchidism in rare syndromes. Part 5 The postnatal effects of cryptorchidism: a primary anomaly or secondary effects?
- endocrine effects
- morphological effects
- fertility
- malignancy. Part 6 Diagnosis of undescended testis: introduction
- aims of clinical examination
- technique of examination
- undescended testis versus retractile testis
- clinical features of ectopic testes
- impalpable testis
- conclusion. Part 7 Operative treatment: planning surgery
- the standard orchidopexy
- unusual findings during orchidopexy
- spermatic cord of inadequate length
- the unilateral impalpable testis
- surgical management in the post-pubertal child
- indications for orchidectomy
- complications. Part 8 Hormonal treatment: historical background
- rationale for treatment
- standard regimes
- does hormonal treatment work?
- possible benefits of hormonal treatment
- why hormonal treatment fails
- conclusions. Part 9 Results of treatment: criteria of assessment
- cosmetic result
- fertility
- malignancy
- conclusions. Part 10 Conclusions and future developments.
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