Animal models of HIV and other retroviral infections

著者

    • Racz, Paul
    • Letvin, Norman L.
    • Gluckman, J. C.

書誌事項

Animal models of HIV and other retroviral infections

editors, Paul Racz, Norman L. Letvin, Jean Claude Gluckman

Karger, c1993

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注記

Includes bibliographical references and index

内容説明・目次

内容説明

Animal models have proven of great importance in clarifying the immunopathogenesis of AIDS. This volume provides a timely description of studies in a diversity of animal models that elucidate important events in the immune containment of HIV infections. These studies involve the use of simian immunodeficiency virus-infected macaques, feline immunodeficiency virus- and feline leukemia virus-infected cats, human immunodeficiency virus-infected chimpanzees, macaques, rabbits and immunodeficient mice, and visna virus-infected sheep. These model systems are described and their unique value in studying AIDS is illustrated. This publication will give immunologists, virologists and pathologists a better understanding of the immune cellular events leading to the progression of AIDS.

目次

  • Latency in lentiviral infections - analysis by polymerase chain reaction in situ, A.T. Haase et al
  • immune responsiveness against the V3 loop of HIV-1 gp 120 and animal models, J.C. Gluckman
  • the T lymphocyte response to HIV - molecular basis for immune recognition and escape, F. Gotch et al
  • the role of cytotoxic T lymphocytes in the immunopathogenesis of SIV-induced disease, N.L. Letvin et al
  • pathogenic mechanisms in HIV and SIV infections, R. Kurth et al
  • pathology of lymphoid system in cynomolgus monkeys infected with SIV[sm], H. Feichtinger et al
  • the thymus in SIV-infection, J. Muller et al
  • cellular and humoral immune responses to poliovirus and tetanus following primary immunization of SIV infected macaques, K.H.G. Mills et al
  • induction of T cell proliferation in rhesus macaques immunized with tween-ether-treated SIV[mac] and loss of proliferative activity after virus infection, G. Voss et al
  • HIV-2 in rhesus monkeys - five-year follow-up, I. Nicol-Jourdain et al
  • pathogenesis of feline immunodeficiency virus infection, J.J. Callanan and O. Jarrett
  • morphologic characterization of the lymph node changes in feline immunodeficiency virus infection as an animal model of AIDS, J.J. Callanan et al
  • characterization of feline leukemia virus infection as an animal model of AIDS, L. Tavares et al
  • CD4 T cell depletion in hu-PBL-SCID mice by Noncytopathic HIV isolates, D.E. Mosier
  • detection by polymerase chain reaction of HIV-1 gag sequences in cells and organs of infected rabbits, M.E. Truckenmiller et al
  • role of the immune response in visna, a lentiviral central nervous system disease of sheep, G. Georgsson et al.

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