Specific interactions and biological recognition processes
著者
書誌事項
Specific interactions and biological recognition processes
CRC Press, c1993
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注記
Includes bibliographical references and index
内容説明・目次
内容説明
Specific Interaction and Biological Recognition Processes is devoted to two major aspects of biological processes: specificity in biological recognition and the recognition processes themselves. Topics covered in specificity include the theoretical basis for specificity in biological recognition; the thermodynamic and chemical equilibrium background; and consideration of the relationship between size of combining sites and specificity. The use of semi-emperical potentials for calculating interaction energies and the potential of quantum chemistry methods for calculating receptor-effector affinities are also discussed.
The various recognition processes described include DNA replication, transcription, translation, enzymatic reactions, transmembrane transport processes, mechanisms of action of hormones and other chemical messengers, and self-nonself recognition in immunology. Specific Interaction and Biological Recognition Processes will be a useful reference for molecular biologists, biochemists, enzymologists, immunologists oncologists, pharmaceutical researchers, and others interested in the topic.
目次
Introduction (N. Voiculetz and Z. Simon). Receptor Ligand Equilibria and Biological Recognition Processes (Z. Simon and I. Motoc). Molecular Basis of Receptor-Ligand Interactions (Z. Simon, I. Motoc, and A. Chiriac). Specificity in Enzymatic Reactions (A. Chiriac and Z. Simon). Specificity in Regulation of Gene Expression (N. Voiculetz). Biopolymer Spatial Configuration and the Fidelity of DNA Replication, Transcription and Translation (N. Voiculetz, S. Vasilescu, M. Marin, and Z. Simon). Specificity in Immune Phenomena (Z. Simon and G. Szegli). Specific Interactions in Ionic Transport through Biological Membranes (M.-L. Flonta). Molecular Recognition during Ligand-Receptor Interactions. Applications in Receptor Mapping (T.I. Oprea and L. Kurunczi). Index.
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